5QAY | | OXA-48 IN COMPLEX WITH COMPOUND 32 | | Descriptor: | Beta-lactamase, 3-(1-methylpyrrol-2-yl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAV | | OXA-48 IN COMPLEX WITH COMPOUND 26B | | Descriptor: | Beta-lactamase, 1,2-ETHANEDIOL, 3-[4-(1~{H}-1,2,3,4-tetrazol-5-yl)phenyl]benzoic acid, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.72 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAD | | OXA-48 IN COMPLEX WITH COMPOUND 8A | | Descriptor: | Beta-lactamase, 3-(2-fluorophenyl)benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAU | | OXA-48 IN COMPLEX WITH COMPOUND 26A | | Descriptor: | Beta-lactamase, CHLORIDE ION, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QB2 | | OXA-48 IN COMPLEX WITH COMPOUND 38 | | Descriptor: | Beta-lactamase, 3-quinolin-6-yl-5-quinolin-7-yl-benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAP | | OXA-48 IN COMPLEX WITH COMPOUND 21A | | Descriptor: | Beta-lactamase, CHLORIDE ION, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QB1 | | OXA-48 IN COMPLEX WITH COMPOUND 36 | | Descriptor: | Beta-lactamase, CHLORIDE ION, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QA7 | | OXA-48 IN COMPLEX WITH COMPOUND 4B | | Descriptor: | Beta-lactamase, 3-(3-hydroxyphenyl)benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.82 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAM | | OXA-48 IN COMPLEX WITH COMPOUND 17 | | Descriptor: | Beta-lactamase, 3-[4-(methylsulfonylamino)phenyl]benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.87 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QA9 | | OXA-48 IN COMPLEX WITH COMPOUND 5 | | Descriptor: | Beta-lactamase, 3-[3-(hydroxymethyl)phenyl]benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAI | | OXA-48 IN COMPLEX WITH COMPOUND 12A | | Descriptor: | Beta-lactamase, 3-(3-methylsulfonylphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAK | | OXA-48 IN COMPLEX WITH COMPOUND 14 | | Descriptor: | Beta-lactamase, 3-[3-(dimethylamino)phenyl]benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAS | | OXA-48 IN COMPLEX WITH COMPOUND 23B | | Descriptor: | Beta-lactamase, 3-[4-(2-acetamidoethyl)phenyl]benzoic acid, 1,2-ETHANEDIOL | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAT | | OXA-48 IN COMPLEX WITH COMPOUND 24 | | Descriptor: | Beta-lactamase, 3-[3-(acetyloxymethyl)phenyl]benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QA4 | | OXA-48 IN COMPLEX WITH COMPOUND 3A | | Descriptor: | Beta-lactamase, 3-(2-methylphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QA5 | | OXA-48 IN COMPLEX WITH COMPOUND 3B | | Descriptor: | Beta-lactamase, 3-(3-methylphenyl)benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QA6 | | OXA-48 IN COMPLEX WITH COMPOUND 4A | | Descriptor: | Beta-lactamase, 3-(2-hydroxyphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAA | | OXA-48 IN COMPLEX WITH COMPOUND 6A | | Descriptor: | Beta-lactamase, 3-(2-methoxyphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-04-11 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAH | | OXA-48 IN COMPLEX WITH COMPOUND 9B | | Descriptor: | Beta-lactamase, 3-(3-methoxycarbonylphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAL | | OXA-48 IN COMPLEX WITH COMPOUND 11B | | Descriptor: | Beta-lactamase, 3-(4-aminocarbonylphenyl)benzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QB0 | | OXA-48 IN COMPLEX WITH COMPOUND 35 | | Descriptor: | Beta-lactamase, 3-pyridin-2-ylbenzoic acid, 1,2-ETHANEDIOL, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QB4 | | OXA-48 IN COMPLEX WITH SUBSTRATE IMIPENEM | | Descriptor: | Beta-lactamase, (5R)-5-[(1S,2R)-1-formyl-2-hydroxypropyl]-3-[(2-{[(E)-iminomethyl]amino}ethyl)sulfanyl]-4,5-dihydro-1H-pyrrole-2-carboxylic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAC | | OXA-48 IN COMPLEX WITH COMPOUND 6C | | Descriptor: | Beta-lactamase, 3-(4-methoxyphenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAJ | | OXA-48 IN COMPLEX WITH COMPOUND 13 | | Descriptor: | Beta-lactamase, 3-(4-aminophenyl)benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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5QAO | | OXA-48 IN COMPLEX WITH COMPOUND 19B | | Descriptor: | Beta-lactamase, 3-[4-(methylsulfonylaminomethyl)phenyl]benzoic acid, CHLORIDE ION, ... | | Authors: | Lund, B.A., Leiros, H.K.S. | | Deposit date: | 2017-07-11 | | Release date: | 2018-01-10 | | Last modified: | 2018-03-14 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | A focused fragment library targeting the antibiotic resistance enzyme - Oxacillinase-48: Synthesis, structural evaluation and inhibitor design.
Eur J Med Chem, 145, 2018
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