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4YV9
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BU of 4yv9 by Molmil
X-ray crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2
Descriptor: Cyclosporin A, SULFATE ION, Transcriptional regulator
Authors:Neiditch, M.B, Parashar, V.
Deposit date:2015-03-19
Release date:2015-04-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Rgg protein structure-function and inhibition by cyclic peptide compounds.
Proc.Natl.Acad.Sci.USA, 112, 2015
4YV6
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BU of 4yv6 by Molmil
X-ray crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2
Descriptor: SULFATE ION, Transcriptional regulator
Authors:Neiditch, M.B, Parashar, V.
Deposit date:2015-03-19
Release date:2015-04-08
Last modified:2017-11-01
Method:X-RAY DIFFRACTION (2.053 Å)
Cite:Rgg protein structure-function and inhibition by cyclic peptide compounds.
Proc.Natl.Acad.Sci.USA, 112, 2015
4Z5H
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BU of 4z5h by Molmil
HipB(S29A)-O2 20mer complex
Descriptor: Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*TP*CP*AP*CP*TP*AP*AP*AP*GP*GP*AP*TP*AP*A)-3')
Authors:Min, J, Brennan, R.G, Schumacher, M.A.
Deposit date:2015-04-02
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Molecular mechanism on hipBA gene regulation.
To be published
4Z5C
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BU of 4z5c by Molmil
HipB-O3 21mer complex
Descriptor: Antitoxin HipB, DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*CP*GP*TP*AP*GP*AP*GP*CP*GP*GP*AP*TP*AP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*A)-3')
Authors:Min, J, Brennan, R.G, Schumacher, M.A.
Deposit date:2015-04-02
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism on hipBA gene regulation.
To be published
4Z59
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BU of 4z59 by Molmil
HipB-O4 20mer complex
Descriptor: Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*GP*AP*TP*CP*GP*CP*GP*GP*AP*TP*AP*A)-3')
Authors:Min, J, Brennan, R.G, Schumacher, M.A.
Deposit date:2015-04-02
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Molecular mechanism on hipBA gene regulation.
To be published
4Z5D
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BU of 4z5d by Molmil
HipB-O4 21mer complex
Descriptor: Antitoxin HipB, DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*GP*CP*GP*AP*TP*CP*GP*CP*GP*GP*AP*TP*A)-3'), DNA (5'-D(*TP*TP*TP*AP*TP*CP*CP*GP*CP*GP*AP*TP*CP*GP*CP*GP*GP*AP*TP*AP*A)-3')
Authors:Min, J, Brennan, R.G, Schumacher, M.A.
Deposit date:2015-04-02
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Molecular mechanism on hipBA gene regulation.
To be published
4Z58
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BU of 4z58 by Molmil
HipB-O3 20mer complex
Descriptor: Antitoxin HipB, DNA (5'-D(*TP*TP*AP*TP*CP*CP*GP*CP*TP*CP*TP*AP*CP*GP*GP*GP*AP*TP*AP*A)-3')
Authors:Min, J, Brennan, R.G, Schumacher, M.A.
Deposit date:2015-04-02
Release date:2016-07-06
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Molecular mechanism on hipBA gene regulation.
To be published
5A7L
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BU of 5a7l by Molmil
TP901-1 CI NTD (res 1-80)
Descriptor: CI
Authors:Frandsen, K.E.H, Rasmussen, K.K, Lo Leggio, L.
Deposit date:2015-07-08
Release date:2016-07-27
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.103 Å)
Cite:Structural and Dynamics Studies of a Truncated Variant of Ci Repressor from Bacteriophage Tp901-1.
Sci.Rep., 6, 2016
5IFG
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BU of 5ifg by Molmil
Crystal structure of HigA-HigB complex from E. Coli
Descriptor: Antitoxin HigA, mRNA interferase HigB
Authors:Yang, J.S, Zhou, K, Gao, z.Q, Liu, Q.S, Dong, Y.H.
Deposit date:2016-02-26
Release date:2017-03-01
Method:X-RAY DIFFRACTION (2.702 Å)
Cite:Structural insight into the E. coli HigBA complex
Biochem. Biophys. Res. Commun., 478, 2016
5JUB
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BU of 5jub by Molmil
Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS.
Descriptor: ComS, Transcriptional regulator, pComX-for, ...
Authors:Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (2.57 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
5JUF
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BU of 5juf by Molmil
Crystal structure of the apo form of ComR from S. thermophilus.
Descriptor: SULFATE ION, Transcriptional regulator
Authors:Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S.
Deposit date:2016-05-10
Release date:2016-10-26
Last modified:2016-12-14
Method:X-RAY DIFFRACTION (1.946 Å)
Cite:Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS.
PLoS Pathog., 12, 2016
5K98
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BU of 5k98 by Molmil
Structure of HipA-HipB-O2-O3 complex
Descriptor: Antitoxin HipB, DNA (5'-D(*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*GP*GP*GP*A)-3'), DNA (5'-D(*TP*CP*CP*CP*TP*AP*TP*CP*CP*CP*CP*TP*TP*AP*AP*GP*GP*GP*GP*AP*TP*AP*G)-3'), ...
Authors:Schumacher, M.
Deposit date:2016-05-31
Release date:2016-06-22
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (3.99 Å)
Cite:HipBA-promoter structures reveal the basis of heritable multidrug tolerance.
Nature, 524, 2015
5TN0
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BU of 5tn0 by Molmil
Solution Structure of the N-terminal DNA-binding domain of the master biofilm-regulator SinR from Bacillus subtilis
Descriptor: HTH-type transcriptional regulator SinR
Authors:Draughn, G.L, Bobay, B.G, Stowe, S.D, Thompson, R.J, Cavanagh, J.
Deposit date:2016-10-13
Release date:2017-10-25
Last modified:2019-12-25
Method:SOLUTION NMR
Cite:The Solution Structures and Interaction of SinR and SinI: Elucidating the Mechanism of Action of the Master Regulator Switch for Biofilm Formation in Bacillus subtilis.
J.Mol.Biol., 2019
5W4N
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BU of 5w4n by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, Transcriptional regulator
Authors:Neiditch, M.B, Khataokar, A.A, Capodagli, G.C.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.198 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
5W4M
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BU of 5w4m by Molmil
Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S)
Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ...
Authors:Capodagli, G.C, Neiditch, M.B.
Deposit date:2017-06-12
Release date:2017-10-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.388 Å)
Cite:Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond.
J. Biol. Chem., 292, 2017
5WOQ
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BU of 5woq by Molmil
Crystal structure of an XRE family protein transcriptional regulator from Mycobacterium smegmatis
Descriptor: Transcriptional regulator ClgR
Authors:Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-08-02
Release date:2017-08-16
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of an XRE family protein transcriptional regulator from Mycobacterium smegmatis
To Be Published
5YCL
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BU of 5ycl by Molmil
Crystal structure of HigBA complex from Shigella flexneri
Descriptor: Antitoxin HigA, mRNA interferase HigB
Authors:Youn, W.S, Seok, S.H, Seo, M.D.
Deposit date:2017-09-07
Release date:2018-09-19
Last modified:2019-09-04
Method:X-RAY DIFFRACTION (3.101 Å)
Cite:Structural changes of antitoxin HigA from Shigella flexneri by binding of its cognate toxin HigB.
Int.J.Biol.Macromol., 130, 2019
6B9T
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BU of 6b9t by Molmil
Crystal structure of MPnS with substrate 2-hydroxyethylphosphonate (2-HEP) and Fe(II) bound
Descriptor: (2-hydroxyethyl)phosphonic acid, FE (III) ION, FORMIC ACID, ...
Authors:Born, D.A, Drennan, C.L.
Deposit date:2017-10-11
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural basis for methylphosphonate biosynthesis.
Science, 358, 2017
6B9S
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BU of 6b9s by Molmil
MPnS crystallized in the absence of substrate
Descriptor: FE (III) ION, Methylphosphonate synthase
Authors:Born, D.A, Drennan, C.L.
Deposit date:2017-10-11
Release date:2017-12-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.373 Å)
Cite:Structural basis for methylphosphonate biosynthesis.
Science, 358, 2017
6F8S
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BU of 6f8s by Molmil
Toxin-Antitoxin complex GraTA
Descriptor: DI(HYDROXYETHYL)ETHER, Putative Killer protein, SULFATE ION, ...
Authors:Talavera, A, Loris, R.
Deposit date:2017-12-13
Release date:2018-07-11
Last modified:2019-03-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT.
Nat Commun, 10, 2019
6CF1
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BU of 6cf1 by Molmil
Proteus vulgaris HigA antitoxin structure
Descriptor: Antitoxin HigA, POTASSIUM ION
Authors:Schureck, M.A, Hoffer, E.D, Ei Cho, S, Dunham, C.M.
Deposit date:2018-02-13
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of transcriptional regulation by the HigA antitoxin.
Mol.Microbiol., 111, 2019
6CHV
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BU of 6chv by Molmil
Proteus vulgaris HigA antitoxin bound to DNA
Descriptor: Antitoxin HigA, MAGNESIUM ION, pHigCryst3, ...
Authors:Schureck, M.A, Hoffer, E.D, Onuoha, N, Dunham, C.M.
Deposit date:2018-02-23
Release date:2019-02-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural basis of transcriptional regulation by the HigA antitoxin.
Mol.Microbiol., 111, 2019
6H4C
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BU of 6h4c by Molmil
A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
Descriptor: DI(HYDROXYETHYL)ETHER, MAGNESIUM ION, NICKEL (II) ION, ...
Authors:Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
Deposit date:2018-07-20
Release date:2019-08-28
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
6H49
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BU of 6h49 by Molmil
A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.
Descriptor: Orf20, SULFATE ION
Authors:Ciges-Tomas, J.R, Alite, C, Bowring, J.Z, Donderis, J, Penades, J.R, Marina, A.
Deposit date:2018-07-20
Release date:2019-08-28
Last modified:2019-10-16
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of a polygamous repressor reveals how phage-inducible chromosomal islands spread in nature.
Nat Commun, 10, 2019
6AF4
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BU of 6af4 by Molmil
Toxin-Antitoxin module from Streptococcus pneumoniae
Descriptor: HigA antitoxin, HigB toxin
Authors:Kang, S.M, Kim, D.H, Jin, C.
Deposit date:2018-08-08
Release date:2019-08-14
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Toxin-Antitoxin module from Streptococcus pneumoniae
To Be Published

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