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5DOT
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BU of 5dot by Molmil
Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), apo form
Descriptor: 1,2-ETHANEDIOL, Carbamoyl-phosphate synthase [ammonia], mitochondrial, ...
Authors:Polo, L.M, de Cima, S, Fita, I, Rubio, V.
Deposit date:2015-09-11
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis.
Sci Rep, 5, 2015
1DV2
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BU of 1dv2 by Molmil
The structure of biotin carboxylase, mutant E288K, complexed with ATP
Descriptor: ADENOSINE-5'-TRIPHOSPHATE, BIOTIN CARBOXYLASE
Authors:Thoden, J.B, Blanchard, C.Z, Holden, H.M, Waldrop, G.L.
Deposit date:2000-01-19
Release date:2000-06-09
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Movement of the biotin carboxylase B-domain as a result of ATP binding.
J.Biol.Chem., 275, 2000
5CSK
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BU of 5csk by Molmil
Crystal structure of yeast acetyl-CoA carboxylase, unbiotinylated
Descriptor: Acetyl-CoA carboxylase
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
8HZ5
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BU of 8hz5 by Molmil
The homodimer of a biotin carboxylase isoform from chloroflexus aurantiacus
Descriptor: Biotin carboxylase
Authors:Shen, J, Wu, W, Xu, X.
Deposit date:2023-01-08
Release date:2024-01-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3 Å)
Cite:Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity.
Mbio, 15, 2024
8HZ4
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BU of 8hz4 by Molmil
The tetrameric structure of biotin carboxylase from Chloroflexus aurantiacus in complex with bicarbonate
Descriptor: Biotin carboxylase
Authors:Shen, J, Wu, W, Xu, X.
Deposit date:2023-01-08
Release date:2024-01-10
Last modified:2024-07-24
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Chloroflexus aurantiacus acetyl-CoA carboxylase evolves fused biotin carboxylase and biotin carboxyl carrier protein to complete carboxylation activity.
Mbio, 15, 2024
8HWL
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BU of 8hwl by Molmil
Human Pyruvate Carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Pyruvate carboxylase, mitochondrial
Authors:Liu, D.S, Su, J.Y.
Deposit date:2022-12-30
Release date:2024-01-31
Method:ELECTRON MICROSCOPY (5.63 Å)
Cite:Human Pyruvate Carboxylase
To Be Published
5DOU
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BU of 5dou by Molmil
Crystal Structure of Human Carbamoyl phosphate synthetase I (CPS1), ligand-bound form
Descriptor: 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:de Cima, S, Polo, L.M, Fita, I, Rubio, V.
Deposit date:2015-09-11
Release date:2015-12-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of human carbamoyl phosphate synthetase: deciphering the on/off switch of human ureagenesis.
Sci Rep, 5, 2015
8SGZ
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BU of 8sgz by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-6-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGX
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BU of 8sgx by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-4-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (10.3 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
8SGY
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BU of 8sgy by Molmil
Leishmania tarentolae propionyl-CoA carboxylase (alpha-5-beta-6)
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Propionyl-coa carboxylase beta chain, putative, ...
Authors:Lee, J.K.J, Liu, Y.T, Hu, J.J, Aphasizheva, I, Aphasizhev, R, Zhou, Z.H.
Deposit date:2023-04-13
Release date:2023-05-17
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (8.62 Å)
Cite:CryoEM reveals oligomeric isomers of a multienzyme complex and assembly mechanics.
J Struct Biol X, 7, 2023
2J9G
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BU of 2j9g by Molmil
Crystal structure of Biotin carboxylase from E. coli in complex with AMPPNP and ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, BIOTIN CARBOXYLASE, MAGNESIUM ION, ...
Authors:Mochalkin, I.
Deposit date:2008-03-21
Release date:2008-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Structural Evidence for Substrate-Induced Synergism and Half-Sites Reactivity in Biotin Carboxylase.
Protein Sci., 17, 2008
5CSL
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BU of 5csl by Molmil
Crystal structure of the 500 kD yeast acetyl-CoA carboxylase holoenzyme dimer
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, Acetyl-CoA carboxylase, COENZYME A
Authors:Wei, J, Tong, L.
Deposit date:2015-07-23
Release date:2015-10-28
Last modified:2022-03-23
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Crystal structure of the 500-kDa yeast acetyl-CoA carboxylase holoenzyme dimer.
Nature, 526, 2015
2GPS
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BU of 2gps by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, E23R mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
2GPW
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BU of 2gpw by Molmil
Crystal Structure of the Biotin Carboxylase Subunit, F363A Mutant, of Acetyl-CoA Carboxylase from Escherichia coli.
Descriptor: Biotin carboxylase
Authors:Shen, Y, Chou, C.Y, Chang, G.G, Tong, L.
Deposit date:2006-04-18
Release date:2006-07-04
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Is dimerization required for the catalytic activity of bacterial biotin carboxylase?
Mol.Cell, 22, 2006
4HR7
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BU of 4hr7 by Molmil
Crystal Structure of Biotin Carboxyl Carrier Protein-Biotin Carboxylase Complex from E.coli
Descriptor: 1,2-ETHANEDIOL, Biotin carboxyl carrier protein of acetyl-CoA carboxylase, Biotin carboxylase, ...
Authors:Broussard, T.C, Kobe, M.J, Pakhomova, S, Neau, D.B, Price, A.E, Champion, T.S, Waldrop, G.L.
Deposit date:2012-10-26
Release date:2013-03-13
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.495 Å)
Cite:The three-dimensional structure of the biotin carboxylase-biotin carboxyl carrier protein complex of E. coli acetyl-CoA carboxylase.
Structure, 21, 2013
1A9X
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BU of 1a9x by Molmil
CARBAMOYL PHOSPHATE SYNTHETASE: CAUGHT IN THE ACT OF GLUTAMINE HYDROLYSIS
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE (LARGE CHAIN), CARBAMOYL PHOSPHATE SYNTHETASE (SMALL CHAIN), ...
Authors:Thoden, J, Holden, H.
Deposit date:1998-04-14
Release date:1998-10-21
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Carbamoyl phosphate synthetase: caught in the act of glutamine hydrolysis.
Biochemistry, 37, 1998
4HNT
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BU of 4hnt by Molmil
crystal structure of F403A mutant of S. aureus Pyruvate carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ...
Authors:Yu, L.P.C, Tong, L.
Deposit date:2012-10-21
Release date:2013-01-16
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Characterizing the Importance of the Biotin Carboxylase Domain Dimer for Staphylococcus aureus Pyruvate Carboxylase Catalysis.
Biochemistry, 52, 2013
3TW6
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BU of 3tw6 by Molmil
Structure of Rhizobium etli pyruvate carboxylase T882A with the allosteric activator, acetyl coenzyme-A
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ...
Authors:St Maurice, M, Kumar, S, Lietzan, A.D.
Deposit date:2011-09-21
Release date:2011-10-19
Last modified:2011-12-28
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Interaction between the biotin carboxyl carrier domain and the biotin carboxylase domain in pyruvate carboxylase from Rhizobium etli.
Biochemistry, 50, 2011
3U9T
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BU of 3u9t by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, free enzyme
Descriptor: Methylcrotonyl-CoA carboxylase, alpha-subunit, beta-subunit
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
3U9S
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BU of 3u9s by Molmil
Crystal structure of P. aeruginosa 3-methylcrotonyl-CoA carboxylase (MCC) 750 kD holoenzyme, CoA complex
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, COENZYME A, Methylcrotonyl-CoA carboxylase, ...
Authors:Huang, C.S, Tong, L.
Deposit date:2011-10-19
Release date:2011-12-14
Last modified:2013-01-23
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:An unanticipated architecture of the 750-kDa {alpha}6{beta}6 holoenzyme of 3-methylcrotonyl-CoA carboxylase
Nature, 481, 2012
1BNC
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BU of 1bnc by Molmil
THREE-DIMENSIONAL STRUCTURE OF THE BIOTIN CARBOXYLASE SUBUNIT OF ACETYL-COA CARBOXYLASE
Descriptor: BIOTIN CARBOXYLASE, PHOSPHATE ION
Authors:Waldrop, G, Rayment, I, Holden, H.M.
Deposit date:1994-07-06
Release date:1995-08-30
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Three-dimensional structure of the biotin carboxylase subunit of acetyl-CoA carboxylase.
Biochemistry, 33, 1994
3VA7
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BU of 3va7 by Molmil
Crystal structure of the Kluyveromyces lactis Urea Carboxylase
Descriptor: 5-(HEXAHYDRO-2-OXO-1H-THIENO[3,4-D]IMIDAZOL-6-YL)PENTANAL, GLYCEROL, KLLA0E08119p, ...
Authors:Fan, C, Xiang, S.
Deposit date:2011-12-29
Release date:2012-02-01
Last modified:2013-07-17
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of urea carboxylase provides insights into the carboxyltransfer reaction
J.Biol.Chem., 287, 2012
1C30
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BU of 1c30 by Molmil
CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-24
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1C3O
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BU of 1c3o by Molmil
CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE
Descriptor: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ...
Authors:Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M.
Deposit date:1999-07-28
Release date:1999-12-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway.
Biochemistry, 38, 1999
1BXR
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BU of 1bxr by Molmil
STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE COMPLEXED WITH THE ATP ANALOG AMPPNP
Descriptor: CARBAMOYL-PHOSPHATE SYNTHASE, CHLORIDE ION, L-ornithine, ...
Authors:Thoden, J.B, Wesenberg, G, Raushel, F.M, Holden, H.M.
Deposit date:1998-10-08
Release date:1999-04-20
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Carbamoyl phosphate synthetase: closure of the B-domain as a result of nucleotide binding.
Biochemistry, 38, 1999

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