Mine: Updated entries

5OVE
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RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH SMALL MOLECULE INHIBITOR COMPOUND 1
Descriptor:Son of sevenless homolog 1, 1,2-ETHANEDIOL, 6,7-dimethoxy-~{N}-[(1~{R})-1-naphthalen-1-ylethyl]quinazolin-4-amine
Authors:Hillig, R.C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C.M., Briem, H., Boemer, U., Weiske, J., Badock, V., Petersen, K., Kahmann, J., Wegener, D., Bohnke, N., Eis, K., Graham, K., Wortmann, L., von Nussbaum, F., Bader, B.
Deposit date:2017-08-28
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5OVF
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RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH SMALL MOLECULE INHIBITOR COMPOUND 17
Descriptor:Son of sevenless homolog 1, 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[3-(1~{H}-pyrazol-4-yl)phenyl]ethyl]quinazolin-4-amine, 1,2-ETHANEDIOL
Authors:Hillig, R.C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C.M., Briem, H., Boemer, U., Weiske, J., Badock, V., Petersen, K., Kahmann, J., Wegener, D., Bohnke, N., Eis, K., Graham, K., Wortmann, L., von Nussbaum, F., Bader, B.
Deposit date:2017-08-28
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.01 Å)
Cite:Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5OVG
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RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH SMALL MOLECULE INHIBITOR COMPOUND 18
Descriptor:Son of sevenless homolog 1, ~{N}-[(1~{R})-1-[5-(6,7-dihydro-5~{H}-pyrrolo[1,2-a]imidazol-3-yl)thiophen-2-yl]ethyl]-6,7-dimethoxy-2-methyl-quinazolin-4-amine, 1,2-ETHANEDIOL
Authors:Hillig, R.C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C.M., Briem, H., Boemer, U., Weiske, J., Badock, V., Petersen, K., Kahmann, J., Wegener, D., Bohnke, N., Eis, K., Graham, K., Wortmann, L., von Nussbaum, F., Bader, B.
Deposit date:2017-08-28
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5OVH
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RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH SMALL MOLECULE INHIBITOR COMPOUND 21
Descriptor:Son of sevenless homolog 1, [2-[5-[(1~{R})-1-[(6,7-dimethoxy-2-methyl-5,8-dihydroquinazolin-4-yl)amino]ethyl]thiophen-2-yl]phenyl]methanol, 1,2-ETHANEDIOL
Authors:Hillig, R.C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C.M., Briem, H., Boemer, U., Weiske, J., Badock, V., Petersen, K., Kahmann, J., Wegener, D., Bohnke, N., Eis, K., Graham, K., Wortmann, L., von Nussbaum, F., Bader, B.
Deposit date:2017-08-28
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5OVI
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RAS GUANINE NUCLEOTIDE EXCHANGE FACTOR SOS1 (REM-CDC25) IN COMPLEX WITH SMALL MOLECULE INHIBITOR BAY-293 (COMPOUND 23)
Descriptor:Son of sevenless homolog 1, 6,7-dimethoxy-2-methyl-~{N}-[(1~{R})-1-[4-[2-(methylaminomethyl)phenyl]thiophen-2-yl]ethyl]quinazolin-4-amine, 1,2-ETHANEDIOL
Authors:Hillig, R.C., Sautier, B., Schroeder, J., Moosmayer, D., Hilpmann, A., Stegmann, C.M., Briem, H., Boemer, U., Weiske, J., Badock, V., Petersen, K., Kahmann, J., Wegener, D., Bohnke, N., Eis, K., Graham, K., Wortmann, L., von Nussbaum, F., Bader, B.
Deposit date:2017-08-28
Release date:2019-02-06
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Discovery of potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5SVB
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MECHANISM OF ATP-DEPENDENT ACETONE CARBOXYLATION, ACETONE CARBOXYLASE AMP BOUND STRUCTURE
Descriptor:Acetone carboxylase alpha subunit, Acetone carboxylase beta subunit, Acetone carboxylase gamma subunit, ...
Authors:Eilers, B.J., Mus, F., Alleman, A.B., Kabasakal, B.V., Murray, J.W., Nocek, B.P., Dubois, J.L., Peters, J.W.
Deposit date:2016-08-05
Release date:2017-08-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.645 Å)
Cite:Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
Sci Rep, 7, 2017
5SVC
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MECHANISM OF ATP-DEPENDENT ACETONE CARBOXYLATION, ACETONE CARBOXYLASE NUCLEOTIDE-FREE STRUCTURE
Descriptor:Acetone carboxylase alpha subunit, Acetone carboxylase beta subunit, Acetone carboxylase gamma subunit, ...
Authors:Eilers, B.J., Mus, F., Alleman, A.B., Kabasakal, B.V., Murray, J.W., Nocek, B.P., Dubois, J.L., Peters, J.W.
Deposit date:2016-08-05
Release date:2017-08-09
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural Basis for the Mechanism of ATP-Dependent Acetone Carboxylation.
Sci Rep, 7, 2017
5T61
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TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, TRICLINIC FORM AT 2.55 A
Descriptor:Tungsten formylmethanofuran dehydrogenase subunit fwdA, Tungsten formylmethanofuran dehydrogenase subunit B, Tungsten-containing formylmethanofuran dehydrogenase 2 subunit C, ...
Authors:Wagner, T., Ermler, U., Shima, S.
Deposit date:2016-09-01
Release date:2016-10-19
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters.
Science, 354, 2016
5TKZ
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MEC-8 N-TERMINAL RRM BOUND TO TANDEM GCAC LIGAND
Descriptor:Mec-8 protein, DNA (5'-D(*AP*GP*CP*AP*CP*AP*TP*TP*TP*TP*TP*TP*TP*TP*AP*GP*CP*AP*CP*A)-3')
Authors:Soufari, H., Mackereth, C.D.
Deposit date:2016-10-10
Release date:2017-01-11
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.529 Å)
Cite:Conserved binding of GCAC motifs by MEC-8, couch potato, and the RBPMS protein family.
RNA, 23, 2017
5TMC
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RE-REFINEMENT OF THERMUS THERMOPILES DNA-DIRECTED RNA POLYMERASE STRUCTURE
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Wang, J.
Deposit date:2016-10-12
Release date:2016-11-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.71 Å)
Cite:On the validation of crystallographic symmetry and the quality of structures.
Protein Sci., 24, 2015
5TMF
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RE-REFINEMENT OF THERMUS THERMOPHILUS RNA POLYMERASE
Descriptor:DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
Authors:Wang, J.
Deposit date:2016-10-12
Release date:2016-11-23
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3 Å)
Cite:On the validation of crystallographic symmetry and the quality of structures.
Protein Sci., 24, 2015
5UCM
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CRYSTAL STRUCTURE OF PROLYL-TRNA SYNTHETASE FROM PSEUDOMONAS AERUGINOSA
Descriptor:Proline--tRNA ligase, MAGNESIUM ION
Authors:Seattle Structural Genomics Center for Infectious Disease, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-12-22
Release date:2017-02-22
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Characterization and structure determination of prolyl-tRNA synthetase from Pseudomonas aeruginosa and development as a screening platform.
Protein Sci., 2019
5UF1
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CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR (VLR) O13 IN COMPLEX WITH H-TRISACCHARIDE
Descriptor:O13, ALPHA-L-FUCOSE, BETA-D-GALACTOSE, ...
Authors:Gunn, R.J., Collins, B.C., McKitrick, T.R., Cummings, R.D., Cooper, M.D., Herrin, B.R., Wilson, I.A.
Deposit date:2017-01-03
Release date:2017-10-18
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5UF4
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CRYSTAL STRUCTURE OF VARIABLE LYMPHOCYTE RECEPTOR (VLR) O13 WITH LNNT BOUND
Descriptor:O13, ALPHA-D-GLUCOSE, BETA-D-GALACTOSE, ...
Authors:Gunn, R.J., Collins, B.C., McKitrick, T.R., Cummings, R.D., Cooper, M.D., Herrin, B.R., Wilson, I.A.
Deposit date:2017-01-03
Release date:2017-10-18
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.04 Å)
Cite:Structural Insights into VLR Fine Specificity for Blood Group Carbohydrates.
Structure, 25, 2017
5UKG
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CRYSTAL STRUCTURE OF THE GENETICALLY ENCODED CALCIUM INDICATOR K-GECO
Descriptor:K-GECO, CALCIUM ION
Authors:Schreiter, E.R.
Deposit date:2017-01-22
Release date:2018-02-07
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:A genetically encoded Ca2+indicator based on circularly permutated sea anemone red fluorescent protein eqFP578.
BMC Biol., 16, 2018
5V0Y
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SOLUTION STRUCTURE OF ARENICIN-3.
Descriptor:arenicin-3
Authors:Edwards, I.A., Mobli, M.
Deposit date:2017-02-28
Release date:2018-08-08
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Solution structure of arenicin-3.
To Be Published
5V11
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SOLUTION STRUCTURE OF ARENICIN-3 SYNTHETIC ANALOG.
Descriptor:AA139
Authors:Edwards, I.A., Mobli, M.
Deposit date:2017-03-01
Release date:2018-08-08
Last modified:2019-02-20
Method:SOLUTION NMR
Cite:Solution structure of arenicin-3 synthetic analog.
To Be Published
5V5S
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MULTI-DRUG EFFLUX; MEMBRANE TRANSPORT; RND SUPERFAMILY; DRUG RESISTANCE
Descriptor:Outer membrane protein TolC, Multidrug efflux pump subunit AcrA, Multidrug efflux pump subunit AcrB
Authors:wang, Z., fan, G., Hryc, C.F., Blaza, J.N., Serysheva, I.I., Schmid, M.F., Chiu, W., Luisi, B.F., Du, D.
Deposit date:2017-03-15
Release date:2017-04-19
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (6.5 Å)
Cite:An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
5V8I
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THERMUS THERMOPHILUS 70S RIBOSOME LACKING RIBOSOMAL PROTEIN US17
Descriptor:23S Ribosomal RNA, 5S Ribosomal RNA, 50S ribosomal protein L2, ...
Authors:Gregory, S.T., Jogl, G.
Deposit date:2017-03-22
Release date:2018-03-28
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Structural robustness of the ribosome inferred from X-ray crystal structures of the 30S ribosomal subunit and the 70S ribosome lacking ribosomal protein uS17
To be published
5VAU
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BCL-2 COMPLEX WITH BECLIN 1 BH3 DOMAIN
Descriptor:Apoptosis regulator Bcl-2 -- Bcl-2-like protein 1 Chimera, Beclin-1
Authors:Lee, E.F., Smith, B.J., Yao, S., Fairlie, W.D.
Deposit date:2017-03-28
Release date:2018-04-04
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Bcl-2 complex with Beclin 1 BH3 domain
To Be Published
5VCM
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ALPHA-1,6-MANNOSYL-GLYCOPROTEIN 2-BETA-N-ACETYLGLUCOSAMINYLTRANSFERASE WITH BOUND UDP AND MANGANESE
Descriptor:Alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE, ...
Authors:Sanders, J.H., Kadirvelraj, R., Wood, Z.A.
Deposit date:2017-03-31
Release date:2018-04-11
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.599 Å)
Cite:HumanN-acetylglucosaminyltransferase II substrate recognition uses a modular architecture that includes a convergent exosite.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5VGC
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CRYSTAL STRUCTURE OF THE NLEG5-1 EFFECTOR (C200A) FROM ESCHERICHIA COLI O157:H7 STR. SAKAI
Descriptor:NleG5-1 effector, CALCIUM ION, CHLORIDE ION, ...
Authors:Borek, D., Valleau, D., Skarina, T., Jobin, M.C., Wawrzak, Z., Anderson, W.F., Savchenko, A., Center for Structural Genomics of Infectious Diseases (CSGID)
Deposit date:2017-04-10
Release date:2018-04-18
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of the NleG5-1 effector (C200A) from Escherichia coli O157:H7 str. Sakai
To Be Published
5VR0
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CRYSTAL STRUCTURE OF GLUCOSE ISOMERASE FROM STREPTOMYCES RUBIGINOSUS
Descriptor:Xylose isomerase, (4R)-2-METHYLPENTANE-2,4-DIOL, MANGANESE (II) ION, ...
Authors:Borek, D., Otwinowski, Z.
Deposit date:2017-05-09
Release date:2018-05-02
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Real-space analysis of radiation-induced specific changes with independent component analysis.
J Synchrotron Radiat, 25, 2018
5VRF
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CRYOEM STRUCTURE OF THE ZINC TRANSPORTER YIIP FROM HELICAL CRYSTALS
Descriptor:Cadmium and zinc efflux pump FieF, ZINC ION
Authors:Coudray, N., Lopez-Redondo, M., Zhang, Z., Alexopoulos, J., Stokes, D.L., Transcontinental EM Initiative for Membrane Protein Structure (TEMIMPS)
Deposit date:2017-05-10
Release date:2018-03-14
Last modified:2019-02-20
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis for the alternating access mechanism of the cation diffusion facilitator YiiP.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
5W5R
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AGROBACTERIUM TUMEFACIENS ADP-GLUCOSE PYROPHOSPHORYLASE P96A MUTANT BOUND TO ACTIVATOR PYRUVATE
Descriptor:Glucose-1-phosphate adenylyltransferase, SULFATE ION, PYRUVIC ACID
Authors:Mascarenhas, R.N., Hill, B.L., Ballicora, M.A., Liu, D.
Deposit date:2017-06-15
Release date:2018-11-14
Last modified:2019-02-20
Method:X-RAY DIFFRACTION (1.754 Å)
Cite:Structural analysis reveals a pyruvate-binding activator site in theAgrobacterium tumefaciensADP-glucose pyrophosphorylase.
J. Biol. Chem., 2018
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