PDB: 280 resultsInfo pagesStatus searchChemie searchBIRD

---

6DXN	1.95 Angstrom Resolution Crystal Structure of DsbA Disulfide Interchange Protein from Klebsiella pneumoniae. Descriptor: TRIETHYLENE GLYCOL, Thiol:disulfide interchange protein Authors: Minasov, G, Wawrzak, Z, Shuvalova, L, Kiryukhina, O, Endres, M, Satchell, K.J.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) Deposit date: 2018-06-29 Release date: 2018-07-11 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (1.95 Å) Cite: A Structural Systems Biology Approach to High-Risk CG23 Klebsiella pneumoniae. Microbiol Resour Announc, 12, 2023
4TKY	The complex structure of E. coli DsbA bound to a peptide at the DsbA/DsbB interface Descriptor: ACETYL GROUP, AMINO GROUP, PRO-PHE-ALA-THR-CYS-ASP-SER, ... Authors: Premkumar, L, Martin, J.L. Deposit date: 2014-05-28 Release date: 2015-01-14 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Peptide Inhibitors of the Escherichia coli DsbA Oxidative Machinery Essential for Bacterial Virulence. J.Med.Chem., 58, 2015
7TTV	E.coli DsbA in complex with 4-phenyl-2-(3-phenylpropyl)thiazole-5-carboxylic acid Descriptor: 4-phenyl-2-(3-phenylpropyl)-1,3-thiazole-5-carboxylic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2022-02-02 Release date: 2023-04-12 Last modified: 2023-10-25 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Methyl probes in proteins for determining ligand binding mode in weak protein-ligand complexes. Sci Rep, 12, 2022
6WHD	Crystal structure of E.coli DsbA in complex with diaryl ether analogue 2 Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [4-(4-cyano-3-methylphenoxy)phenyl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-04-08 Release date: 2020-06-24 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Rapid Elaboration of Fragments into Leads by X-ray Crystallographic Screening of Parallel Chemical Libraries (REFiLX). J.Med.Chem., 63, 2020
4DVC	Structural and functional studies of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera toxin production Descriptor: DIMETHYL SULFOXIDE, SULFATE ION, Thiol:disulfide interchange protein DsbA Authors: Walden, P.M, Martin, J.L. Deposit date: 2012-02-23 Release date: 2012-10-31 Method: X-RAY DIFFRACTION (1.2 Å) Cite: The 1.2 A resolution crystal structure of TcpG, the Vibrio cholerae DsbA disulfide-forming protein required for pilus and cholera-toxin production Acta Crystallogr.,Sect.D, 68, 2012
1R4W	Crystal structure of Mitochondrial class kappa glutathione transferase Descriptor: GLUTATHIONE, Glutathione S-transferase, mitochondrial Authors: Ladner, J.E, Parsons, J.F, Rife, C.L, Gilliland, G.L, Armstrong, R.N. Deposit date: 2003-10-08 Release date: 2004-02-03 Last modified: 2024-02-14 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Parallel Evolutionary Pathways for Glutathione Transferases: Structure and Mechanism of the Mitochondrial Class Kappa Enzyme rGSTK1-1 Biochemistry, 43, 2004
1BED	STRUCTURE OF DISULFIDE OXIDOREDUCTASE Descriptor: DSBA OXIDOREDUCTASE Authors: Hu, S.-H, Martin, J.L. Deposit date: 1996-09-16 Release date: 1997-10-08 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2 Å) Cite: Structure of TcpG, the DsbA protein folding catalyst from Vibrio cholerae. J.Mol.Biol., 268, 1997
1BQ7	DSBA MUTANT P151A, ROLE OF THE CIS-PROLINE IN THE ACTIVE SITE OF DSBA Descriptor: PROTEIN (DISULFIDE OXIDOREDUCTASE) Authors: Charbonnier, J.-B, Stura, E.A. Deposit date: 1998-08-21 Release date: 1999-08-20 Last modified: 2023-08-09 Method: X-RAY DIFFRACTION (2.8 Å) Cite: On the role of the cis-proline residue in the active site of DsbA. Protein Sci., 8, 1999
5HFI	Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa with GSH Descriptor: GLUTATHIONE, Uncharacterized protein, cytosolic disulfide reductase DsbM Authors: Jo, I, Ha, N.-C. Deposit date: 2016-01-07 Release date: 2016-10-26 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.801 Å) Cite: Crystal structures of the disulfide reductase DsbM from Pseudomonas aeruginosa Acta Crystallogr D Struct Biol, 72, 2016
5TLQ	Model structure of the oxidized PaDsbA1 and 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine complex Descriptor: 3-[(2-methylbenzyl)sulfanyl]-4H-1,2,4-triazol-4-amine, Thiol:disulfide interchange protein DsbA Authors: Mohanty, B, Rimmer, K.A, McMahon, R.M, Headey, S.J, Vazirani, M, Shouldice, S.R, Coincon, M, Tay, S, Morton, C.J, Simpson, J.S, Martin, J.L, Scanlon, M.S. Deposit date: 2016-10-11 Release date: 2017-04-12 Last modified: 2023-06-14 Method: SOLUTION NMR Cite: Fragment library screening identifies hits that bind to the non-catalytic surface of Pseudomonas aeruginosa DsbA1. PLoS ONE, 12, 2017
5HFG	Cytosolic disulfide reductase DsbM from Pseudomonas aeruginosa Descriptor: Uncharacterized protein, cytosolic disulfide reductase DsbM Authors: Jo, I, Ha, N.-C. Deposit date: 2016-01-07 Release date: 2016-10-26 Last modified: 2023-11-08 Method: X-RAY DIFFRACTION (1.823 Å) Cite: Crystal structures of the disulfide reductase DsbM from Pseudomonas aeruginosa Acta Crystallogr D Struct Biol, 72, 2016
7DKA	Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, C24S mutant protein Descriptor: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Kim, M.-K, Zhang, J, Zhao, L. Deposit date: 2020-11-23 Release date: 2021-11-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.56 Å) Cite: Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein To Be Published
7DK9	Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein Descriptor: DI(HYDROXYETHYL)ETHER, DSBA domain-containing protein, PHOSPHATE ION Authors: Kim, M.-K, Zhang, J, Zhao, L. Deposit date: 2020-11-23 Release date: 2021-11-24 Method: X-RAY DIFFRACTION (1.72 Å) Cite: Crystal structure of DsbA-like protein DR2335 from Deinococcus radiodurans R1, native protein To Be Published
5VYO	The complex structure of Burkholderia pseudomallei DsbA bound to a peptide Descriptor: Disulfide bond formation protein B, Thiol:disulfide interchange protein Authors: McMahon, R.M, Martin, J.L. Deposit date: 2017-05-25 Release date: 2018-03-21 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.49 Å) Cite: Virulence of the Melioidosis Pathogen Burkholderia pseudomallei Requires the Oxidoreductase Membrane Protein DsbB. Infect. Immun., 86, 2018
3L9S	Crystal Structure of Salmonella enterica serovar Typhimurium DsbA Descriptor: Thiol:disulfide interchange protein Authors: Heras, B, Jarrott, R, Shouldice, S.R, Guncar, G. Deposit date: 2010-01-05 Release date: 2010-03-09 Last modified: 2023-11-01 Method: X-RAY DIFFRACTION (1.58 Å) Cite: Structural and functional characterization of three DsbA paralogues from Salmonella enterica serovar typhimurium J.Biol.Chem., 285, 2010
6XSP	Crystal structure of E.coli DsbA in complex with 2-(2,6-bis(3-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [2,6-bis(3-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-15 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XSQ	Crystal structure of E.coli DsbA in complex with 2-(6-(3-methoxyphenyl)-2-(4-methoxyphenyl)benzofuran-3-yl)acetic acid Descriptor: COPPER (II) ION, Thiol:disulfide interchange protein DsbA, [6-(3-methoxyphenyl)-2-(4-methoxyphenyl)-1-benzofuran-3-yl]acetic acid Authors: Wang, G, Heras, B. Deposit date: 2020-07-16 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
6XT3	Crystal structure of E.coli DsbA in complex with 3-(3-(carboxymethyl)-6-(3-methoxyphenyl)benzofuran-2-yl)benzoic acid Descriptor: 3-[3-(carboxymethyl)-6-(3-methoxyphenyl)-1-benzofuran-2-yl]benzoic acid, COPPER (II) ION, Thiol:disulfide interchange protein DsbA Authors: Wang, G, Heras, B. Deposit date: 2020-07-17 Release date: 2021-08-11 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (1.99 Å) Cite: Elaboration of a benzofuran scaffold and evaluation of binding affinity and inhibition of Escherichia coli DsbA: A fragment-based drug design approach to novel antivirulence compounds. Bioorg.Med.Chem., 45, 2021
1YZX	Crystal structure of human kappa class glutathione transferase Descriptor: Glutathione S-transferase kappa 1, L-GAMMA-GLUTAMYL-3-SULFINO-L-ALANYLGLYCINE Authors: Li, J, Xia, Z, Ding, J. Deposit date: 2005-02-28 Release date: 2005-11-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (1.93 Å) Cite: Thioredoxin-like domain of human kappa class glutathione transferase reveals sequence homology and structure similarity to the theta class enzyme PROTEIN SCI., 14, 2005
1TI1	crystal structure of a mutant DsbA Descriptor: DODECANE, Thiol:disulfide interchange protein dsbA Authors: Kone, A, Serre, L. Deposit date: 2004-06-02 Release date: 2005-05-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant. J.Mol.Biol., 347, 2005
1DSB	CRYSTAL STRUCTURE OF THE DSBA PROTEIN REQUIRED FOR DISULPHIDE BOND FORMATION IN VIVO Descriptor: DSBA Authors: Martin, J.L, Bardwell, J.C.A, Kuriyan, J. Deposit date: 1993-05-24 Release date: 1994-01-31 Last modified: 2011-07-13 Method: X-RAY DIFFRACTION (2 Å) Cite: Crystal structure of the DsbA protein required for disulphide bond formation in vivo. Nature, 365, 1993
1U3A	mutant DsbA Descriptor: 3,6,9,12,15,18,21,24-OCTAOXAHEXACOSAN-1-OL, Thiol: disulfide interchange protein dsbA Authors: Serre, L. Deposit date: 2004-07-21 Release date: 2005-05-03 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (2 Å) Cite: Intriguing conformation changes associated with the trans/cis isomerization of a prolyl residue in the active site of the DsbA C33A mutant J.Mol.Biol., 347, 2005
3C7M	Crystal structure of reduced DsbL Descriptor: CADMIUM ION, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... Authors: Stirnimann, C.U, Grimshaw, J.P.A, Glockshuber, R, Grutter, M.G, Capitani, G. Deposit date: 2008-02-07 Release date: 2008-07-15 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (1.55 Å) Cite: DsbL and DsbI form a specific dithiol oxidase system for periplasmic arylsulfate sulfotransferase in uropathogenic Escherichia coli. J.Mol.Biol., 380, 2008
1UN2	Crystal structure of circularly permuted CPDSBA_Q100T99: Preserved Global Fold and Local Structural Adjustments Descriptor: THIOL-DISULFIDE INTERCHANGE PROTEIN Authors: Manjasetty, B.A, Hennecke, J, Glockshuber, R, Heinemann, U. Deposit date: 2003-09-03 Release date: 2003-09-26 Last modified: 2023-12-13 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structure of Circularly Permuted Dsba(Q100T99): Preserved Global Fold and Local Structural Adjustments Acta Crystallogr.,Sect.D, 60, 2004
2B3S	structure of the DSBA mutant (P31G-C33A) Descriptor: Thiol:disulfide interchange protein dsbA Authors: Vives, C, Royant, A, Serre, L. Deposit date: 2005-09-21 Release date: 2006-09-05 Last modified: 2023-08-23 Method: X-RAY DIFFRACTION (1.96 Å) Cite: Structure of the DSBA mutant (P31G-C33A) To be Published

 

123456789101112>