PDB: 167 件ウェブページステータス検索Chemie searchBIRD

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7MD2	The F1 region of ammocidin-bound Saccharomyces cerevisiae ATP synthase 分子名称: (3~{E},5~{Z},7~{E},9~{R},10~{S},11~{E},13~{E},15~{E},17~{R},18~{S},20~{S})-20-[(1~{R})-1-[(2~{S},3~{R},4~{R},5~{S},6~{R})-5-[(2~{S},4~{S},5~{S},6~{R})-5-[(2~{S},4~{R},5~{R},6~{R})-4,6-dimethyl-4,5-bis(oxidanyl)oxan-2-yl]oxy-6-methyl-4-oxidanyl-oxan-2-yl]oxy-3-methoxy-6-(3-methoxypropyl)-5-methyl-2,4-bis(oxidanyl)oxan-2-yl]ethyl]-5,18-dimethoxy-3,7,9,11,13,15-hexamethyl-10-[(2~{R},3~{S},4~{R},5~{R},6~{S})-6-methyl-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13,15-hexaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... 著者 Guo, H, Rubinstein, J.L. 登録日 2021-04-03 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia Biorxiv, 2021
7MD3	The F1 region of apoptolidin-bound Saccharomyces cerevisiae ATP synthase 分子名称: (3~{E},5~{E},7~{E},9~{R},10~{R},11~{E},13~{E},17~{S},18~{S},20~{S})-18-methoxy-20-[(~{R})-[(2~{R},3~{R},4~{S},5~{R},6~{R})-6-[(2~{R})-3-methoxy-2-[(2~{R},4~{S},5~{S},6~{S})-5-[(2~{S},4~{R},5~{R},6~{R})-4-methoxy-6-methyl-5-oxidanyl-oxan-2-yl]oxy-4,6-dimethyl-4-oxidanyl-oxan-2-yl]oxy-propyl]-3,5-dimethyl-2,4-bis(oxidanyl)oxan-2-yl]-oxidanyl-methyl]-10-[(2~{R},3~{S},4~{S},5~{R},6~{S})-5-methoxy-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-3,5,7,9,13-pentamethyl-17-oxidanyl-1-oxacycloicosa-3,5,7,11,13-pentaen-2-one, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... 著者 Guo, H, Rubinstein, J.L. 登録日 2021-04-03 公開日 2021-08-11 最終更新日 2024-05-29 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 A Family of Glycosylated Macrolides Selectively Target Energetic Vulnerabilities in Leukemia Biorxiv, 2021
2XOK	Refined structure of yeast F1c10 ATPase complex to 3 A resolution 分子名称: ATP SYNTHASE, ATP SYNTHASE CATALYTIC SECTOR F1 EPSILON SUBUNIT, ATP SYNTHASE SUBUNIT 9, ... 著者 Stock, D, W Leslie, A.G, Walker, J.E. 登録日 2010-08-18 公開日 2010-09-22 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Molecular architecture of the rotary motor in ATP synthase. Science, 286, 1999
1H8E	(ADP.AlF4)2(ADP.SO4) bovine F1-ATPase (all three catalytic sites occupied) 分子名称: ADENOSINE-5'-DIPHOSPHATE, BOVINE MITOCHONDRIAL F1-ATPASE, GLYCEROL, ... 著者 Menz, R.I, Walker, J.E, Leslie, A.G.W. 登録日 2001-02-02 公開日 2001-08-10 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of Bovine Mitochondrial F1-ATPase with Nucleotide Bound to All Three Catalytic Sites: Implications for the Mechanism of Rotary Catalysis Cell(Cambridge,Mass.), 106, 2001
6F5D	Trypanosoma brucei F1-ATPase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP synthase gamma subunit, ATP synthase subunit alpha, ... 著者 Montgomery, M.G, Gahura, O, Leslie, A.G.W, Zikova, A, Walker, J.E. 登録日 2017-12-01 公開日 2018-02-21 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 ATP synthase fromTrypanosoma bruceihas an elaborated canonical F1-domain and conventional catalytic sites. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1E79	Bovine F1-ATPase inhibited by DCCD (dicyclohexylcarbodiimide) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP SYNTHASE ALPHA CHAIN HEART ISOFORM, ... 著者 Gibbons, C, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. 登録日 2000-08-25 公開日 2000-11-03 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 The Structure of the Central Stalk in Bovine F(1)-ATPase at 2.4 A Resolution. Nat.Struct.Biol., 7, 2000
2CK3	Azide inhibited bovine F1-ATPase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ATP SYNTHASE SUBUNIT ALPHA, MITOCHONDRIAL, ... 著者 Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. 登録日 2006-04-10 公開日 2006-05-08 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 How Azide Inhibits ATP Hydrolysis by the F-Atpases. Proc.Natl.Acad.Sci.USA, 103, 2006
2XND	Crystal structure of bovine F1-c8 sub-complex of ATP Synthase 分子名称: ATP SYNTHASE LIPID-BINDING PROTEIN, MITOCHONDRIAL, ATP SYNTHASE SUBUNIT ALPHA, ... 著者 Watt, I.N, Montgomery, M.G, Runswick, M.J, Leslie, A.G.W, Walker, J.E. 登録日 2010-08-02 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Bioenergetic Cost of Making an Adenosine Triphosphate Molecule in Animal Mitochondria. Proc.Natl.Acad.Sci.USA, 107, 2010
3FKS	Yeast F1 ATPase in the absence of bound nucleotides 分子名称: ATP synthase subunit alpha, mitochondrial, ATP synthase subunit beta, ... 著者 Kabaleeswaran, V, Symersky, J, Shen, H, Walker, J.E, Leslie, A.G.W, Mueller, D.M. 登録日 2008-12-17 公開日 2009-03-03 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.587 Å) 主引用文献 Asymmetric structure of the yeast f1 ATPase in the absence of bound nucleotides. J.Biol.Chem., 284, 2009
6B8H	Mosaic model of yeast mitochondrial ATP synthase monomer 分子名称: AATP synthase subunit g, ATP synthase catalytic sector F1 epsilon subunit, ATP synthase protein 8, ... 著者 Guo, H, Bueler, S.A, Rubinstein, J.L. 登録日 2017-10-07 公開日 2018-01-17 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Atomic model for the dimeric FO region of mitochondrial ATP synthase. Science, 358, 2017
5FIL	Bovine mitochondrial ATP synthase state 3b 分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... 著者 Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. 登録日 2015-09-28 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.1 Å) 主引用文献 Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015
5FIJ	Bovine mitochondrial ATP synthase state 2c 分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... 著者 Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. 登録日 2015-09-28 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (7.4 Å) 主引用文献 Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015
5FIK	Bovine mitochondrial ATP synthase state 3a 分子名称: ATP SYNTHASE F(0) COMPLEX SUBUNIT B1, MITOCHONDRIAL, ATP SYNTHASE F(0) COMPLEX SUBUNIT C1, ... 著者 Zhou, A, Rohou, A, Schep, D.G, Bason, J.V, Montgomery, M.G, Walker, J.E, Grigorieff, N, Rubinstein, J.L. 登録日 2015-09-28 公開日 2015-10-14 最終更新日 2024-05-08 実験手法 ELECTRON MICROSCOPY (6.4 Å) 主引用文献 Structure and conformational states of the bovine mitochondrial ATP synthase by cryo-EM. Elife, 4, 2015
6CP3	Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc with inhibitor of oligomycin bound. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... 著者 Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. 登録日 2018-03-13 公開日 2018-04-11 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
8KHF	Structure of the human ATP synthase bound to bedaquiline (membrane domain) 分子名称: ATP synthase F(0) complex subunit B1, mitochondrial, ATP synthase F(0) complex subunit C1, ... 著者 Lai, Y, Zhang, Y. 登録日 2023-08-21 公開日 2024-05-01 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
8KI3	Structure of the human ATP synthase bound to bedaquiline (composite) 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F(0) complex subunit B1, ... 著者 Lai, Y, Zhang, Y, Gong, H. 登録日 2023-08-22 公開日 2024-05-01 最終更新日 2024-08-21 実験手法 ELECTRON MICROSCOPY (2.89 Å) 主引用文献 Inhibition of M. tuberculosis and human ATP synthase by BDQ and TBAJ-587. Nature, 631, 2024
6CP6	Monomer yeast ATP synthase (F1Fo) reconstituted in nanodisc. 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase protein 8, ... 著者 Srivastava, A.P, Luo, M, Symersky, J, Liao, M.F, Mueller, D.M. 登録日 2018-03-13 公開日 2018-04-11 最終更新日 2020-10-14 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 High-resolution cryo-EM analysis of the yeast ATP synthase in a lipid membrane. Science, 360, 2018
5LQY	Structure of F-ATPase from Pichia angusta, in state2 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase OSCP subunit, ... 著者 Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. 登録日 2016-08-17 公開日 2016-11-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.8 Å) 主引用文献 Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2HLD	Crystal structure of yeast mitochondrial F1-ATPase 分子名称: ATP synthase alpha chain, mitochondrial, ATP synthase beta chain, ... 著者 Kabaleeswaran, V, Puri, N, Walker, J.E, Leslie, A.G, Mueller, D.M. 登録日 2006-07-06 公開日 2006-11-28 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Novel features of the rotary catalytic mechanism revealed in the structure of yeast F(1) ATPase. Embo J., 25, 2006
5LQX	Structure of F-ATPase from Pichia angusta, state3 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase AAP1 subunit, ... 著者 Vinothkumar, K.R, Montgomery, M.G, Liu, S, Walker, J.E. 登録日 2016-08-17 公開日 2016-11-16 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (7.9 Å) 主引用文献 Structure of the mitochondrial ATP synthase fromPichia angustadetermined by electron cryo-microscopy. Proc. Natl. Acad. Sci. U.S.A., 113, 2016
2JDI	Ground state structure of F1-ATPase from bovine heart mitochondria (Bovine F1-ATPase crystallised in the absence of azide) 分子名称: ATP SYNTHASE DELTA CHAIN, ATP SYNTHASE EPSILON CHAIN, ATP SYNTHASE GAMMA CHAIN, ... 著者 Bowler, M.W, Montgomery, M.G, Leslie, A.G.W, Walker, J.E. 登録日 2007-01-09 公開日 2007-03-13 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Ground State Structure of F1-ATPase from Bovine Heart Mitochondria at 1.9 A Resolution J.Biol.Chem., 282, 2007
6J5I	Cryo-EM structure of the mammalian DP-state ATP synthase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... 著者 Gu, J, Zhang, L, Yi, J, Yang, M. 登録日 2019-01-11 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.34 Å) 主引用文献 Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
6J5K	Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit alpha, ... 著者 Gu, J, Zhang, L, Yi, J, Yang, M. 登録日 2019-01-11 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (6.2 Å) 主引用文献 Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
6J5J	Cryo-EM structure of the mammalian E-state ATP synthase 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase F1 subunit epsilon, ... 著者 Gu, J, Zhang, L, Yi, J, Yang, M. 登録日 2019-01-11 公開日 2019-06-26 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (3.45 Å) 主引用文献 Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1. Science, 364, 2019
3OEH	Structure of four mutant forms of yeast F1 ATPase: beta-V279F 分子名称: ATP synthase subunit alpha, ATP synthase subunit beta, ATP synthase subunit delta, ... 著者 Arsenieva, D, Symersky, J, Wang, Y, Pagadala, V, Mueller, D.M. 登録日 2010-08-12 公開日 2010-09-15 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structures of mutant forms of the yeast f1 ATPase reveal two modes of uncoupling. J.Biol.Chem., 285, 2010

 

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