Summary
Title: | Crystal structure of thrombin in complex with a novel glucose-conjugated potent inhibitor |
Citation: | Belviso, B.D.,Caliandro, R.,de Candia, M.,Zaetta, G.,Lopopolo, G.,Incampo, F.,Colucci, M.,Altomare, C.D. How a beta-d-Glucoside Side Chain Enhances Binding Affinity to Thrombin of Inhibitors Bearing 2-Chlorothiophene as P1 Moiety: Crystallography, Fragment Deconstruction Study, and Evaluation of Antithrombotic Properties. J.Med.Chem., 57:8563-8575, 2014 PubMed: 25268757DOI: 10.1021/jm5010754 |
Experimental method: | X-RAY DIFFRACTION (1.94 Å) |
Deposition date: | 2013-10-07 |
Release date: | 2013-10-30 |
Obsoletion date: | 2017-12-13 |
Timeline
Downloads
ファイル形式 | ファイル名 (ファイルサイズ) | ||
PDBx/mmCIF | 4n3l.cif.gz 画面表示(71.16 KB) 4n3l.cif | ||
PDBML | 全ての情報 | 4n3l.xml.gz 画面表示(95.28 KB) 4n3l.xml | |
PDB | pdb4n3l.ent.gz 画面表示(56.51 KB) pdb4n3l.ent | ||
構造因子 | r4n3lsf.ent.gz 画面表示(422.00 KB) r4n3lsf.ent |