6J26
Crystal structure of the branched-chain polyamine synthase from Thermococcus kodakarensis (Tk-BpsA) in complex with N4-bis(aminopropyl)spermidine and 5'-methylthioadenosine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006596 | biological_process | polyamine biosynthetic process |
| A | 0009058 | biological_process | biosynthetic process |
| A | 0016740 | molecular_function | transferase activity |
| A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006596 | biological_process | polyamine biosynthetic process |
| B | 0009058 | biological_process | biosynthetic process |
| B | 0016740 | molecular_function | transferase activity |
| B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 18 |
| Details | binding site for residue MTA A 401 |
| Chain | Residue |
| A | PHE125 |
| A | ASP206 |
| A | LEU207 |
| A | ARG208 |
| A | ASP225 |
| A | PRO227 |
| A | PHE236 |
| A | LEU342 |
| A | TYR343 |
| A | B5L402 |
| A | ASP126 |
| A | GLN127 |
| A | ASP158 |
| A | ASP159 |
| A | ASP179 |
| A | ILE180 |
| A | LEU184 |
| A | PHE205 |
| site_id | AC2 |
| Number of Residues | 16 |
| Details | binding site for residue B5L A 402 |
| Chain | Residue |
| A | ASP126 |
| A | ALA128 |
| A | ASP159 |
| A | ASP160 |
| A | ASP225 |
| A | PRO226 |
| A | GLU228 |
| A | GLY254 |
| A | THR256 |
| A | GLU259 |
| A | TYR290 |
| A | TYR295 |
| A | TYR316 |
| A | THR350 |
| A | MTA401 |
| A | HOH560 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue FE A 403 |
| Chain | Residue |
| A | CYS91 |
| A | CYS94 |
| B | CYS91 |
| B | CYS94 |
| site_id | AC4 |
| Number of Residues | 18 |
| Details | binding site for residue MTA B 401 |
| Chain | Residue |
| B | PHE125 |
| B | ASP126 |
| B | GLN127 |
| B | ASP158 |
| B | ASP159 |
| B | ASP179 |
| B | ILE180 |
| B | LEU184 |
| B | PHE205 |
| B | ASP206 |
| B | LEU207 |
| B | ARG208 |
| B | ASP225 |
| B | PRO227 |
| B | PHE236 |
| B | LEU342 |
| B | TYR343 |
| B | B5L402 |
| site_id | AC5 |
| Number of Residues | 16 |
| Details | binding site for residue B5L B 402 |
| Chain | Residue |
| B | ASP126 |
| B | ALA128 |
| B | ASP159 |
| B | ASP160 |
| B | ASP225 |
| B | PRO226 |
| B | GLU228 |
| B | GLY254 |
| B | THR256 |
| B | GLU259 |
| B | TYR290 |
| B | TYR295 |
| B | TYR316 |
| B | THR350 |
| B | MTA401 |
| B | HOH534 |
