6E3E
Structure of RORgt in complex with a novel inverse agonist.
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003677 | molecular_function | DNA binding |
| A | 0004879 | molecular_function | nuclear receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0003677 | molecular_function | DNA binding |
| B | 0004879 | molecular_function | nuclear receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 3 |
| 詳細 | binding site for residue SO4 A 501 |
| 鎖名 | 残基 |
| A | HIS451 |
| A | LEU463 |
| B | HIS451 |
| site_id | AC2 |
| 残基数 | 4 |
| 詳細 | binding site for residue MPD A 502 |
| 鎖名 | 残基 |
| A | GLU290 |
| A | GLU304 |
| A | TYR308 |
| A | LYS311 |
| site_id | AC3 |
| 残基数 | 12 |
| 詳細 | binding site for residue HQ7 A 503 |
| 鎖名 | 残基 |
| A | HIS323 |
| A | LEU324 |
| A | VAL361 |
| A | ARG364 |
| A | MET365 |
| A | ALA368 |
| A | PHE377 |
| A | PHE378 |
| A | GLU379 |
| A | HOH603 |
| A | GLN286 |
| A | CYS320 |
| site_id | AC4 |
| 残基数 | 1 |
| 詳細 | binding site for residue SO4 B 501 |
| site_id | AC5 |
| 残基数 | 4 |
| 詳細 | binding site for residue MPD B 502 |
| 鎖名 | 残基 |
| B | GLU290 |
| B | GLU304 |
| B | LYS311 |
| B | ARG319 |
| site_id | AC6 |
| 残基数 | 11 |
| 詳細 | binding site for residue HQ7 B 503 |
| 鎖名 | 残基 |
| B | CYS320 |
| B | HIS323 |
| B | LEU324 |
| B | VAL361 |
| B | MET365 |
| B | ALA368 |
| B | PHE377 |
| B | PHE378 |
| B | GLU379 |
| B | ILE400 |
| B | HOH620 |
