5ZYL

Crystal structure of CERT START domain in complex with compound E25A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008289	molecular_function	lipid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	13
Details	binding site for residue 9MC A 600

Chain	Residue
A	PHE436
A	GLU575
A	TYR576
A	HOH729
A	HOH901
A	GLU446
A	THR448
A	GLN467
A	HIS469
A	ASN504
A	VAL525
A	TYR553
A	VAL571

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site_id	AC2
Number of Residues	9
Details	binding site for residue GOL A 601

Chain	Residue
A	LEU383
A	ILE528
A	CYS529
A	GLN530
A	LYS550
A	ILE551
A	THR552
A	HOH737
A	HOH804

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:18184806, ECO:0000269|PubMed:20036255

Chain	Residue	Details
A	VAL472
A	THR493
A	GLN530
A	PHE579

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	GLU372

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site_id	SWS_FT_FI3
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	GLU373
A	THR380

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site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648

Chain	Residue	Details
A	ASN377

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