Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

4ZC1

Crystal Structure of type II Dehydroquinate dehydratase from Acinetobacter baumannii with a different crystal form at 2.52 A Resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003855	molecular_function	3-dehydroquinate dehydratase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009073	biological_process	aromatic amino acid family biosynthetic process
A	0009423	biological_process	chorismate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0019631	biological_process	quinate catabolic process
B	0003855	molecular_function	3-dehydroquinate dehydratase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009073	biological_process	aromatic amino acid family biosynthetic process
B	0009423	biological_process	chorismate biosynthetic process
B	0016829	molecular_function	lyase activity
B	0019631	biological_process	quinate catabolic process
C	0003855	molecular_function	3-dehydroquinate dehydratase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009073	biological_process	aromatic amino acid family biosynthetic process
C	0009423	biological_process	chorismate biosynthetic process
C	0016829	molecular_function	lyase activity
C	0019631	biological_process	quinate catabolic process
D	0003855	molecular_function	3-dehydroquinate dehydratase activity
D	0008652	biological_process	amino acid biosynthetic process
D	0009073	biological_process	aromatic amino acid family biosynthetic process
D	0009423	biological_process	chorismate biosynthetic process
D	0016829	molecular_function	lyase activity
D	0019631	biological_process	quinate catabolic process
E	0003855	molecular_function	3-dehydroquinate dehydratase activity
E	0008652	biological_process	amino acid biosynthetic process
E	0009073	biological_process	aromatic amino acid family biosynthetic process
E	0009423	biological_process	chorismate biosynthetic process
E	0016829	molecular_function	lyase activity
E	0019631	biological_process	quinate catabolic process
F	0003855	molecular_function	3-dehydroquinate dehydratase activity
F	0008652	biological_process	amino acid biosynthetic process
F	0009073	biological_process	aromatic amino acid family biosynthetic process
F	0009423	biological_process	chorismate biosynthetic process
F	0016829	molecular_function	lyase activity
F	0019631	biological_process	quinate catabolic process
G	0003855	molecular_function	3-dehydroquinate dehydratase activity
G	0008652	biological_process	amino acid biosynthetic process
G	0009073	biological_process	aromatic amino acid family biosynthetic process
G	0009423	biological_process	chorismate biosynthetic process
G	0016829	molecular_function	lyase activity
G	0019631	biological_process	quinate catabolic process
H	0003855	molecular_function	3-dehydroquinate dehydratase activity
H	0008652	biological_process	amino acid biosynthetic process
H	0009073	biological_process	aromatic amino acid family biosynthetic process
H	0009423	biological_process	chorismate biosynthetic process
H	0016829	molecular_function	lyase activity
H	0019631	biological_process	quinate catabolic process
I	0003855	molecular_function	3-dehydroquinate dehydratase activity
I	0008652	biological_process	amino acid biosynthetic process
I	0009073	biological_process	aromatic amino acid family biosynthetic process
I	0009423	biological_process	chorismate biosynthetic process
I	0016829	molecular_function	lyase activity
I	0019631	biological_process	quinate catabolic process
J	0003855	molecular_function	3-dehydroquinate dehydratase activity
J	0008652	biological_process	amino acid biosynthetic process
J	0009073	biological_process	aromatic amino acid family biosynthetic process
J	0009423	biological_process	chorismate biosynthetic process
J	0016829	molecular_function	lyase activity
J	0019631	biological_process	quinate catabolic process
K	0003855	molecular_function	3-dehydroquinate dehydratase activity
K	0008652	biological_process	amino acid biosynthetic process
K	0009073	biological_process	aromatic amino acid family biosynthetic process
K	0009423	biological_process	chorismate biosynthetic process
K	0016829	molecular_function	lyase activity
K	0019631	biological_process	quinate catabolic process
L	0003855	molecular_function	3-dehydroquinate dehydratase activity
L	0008652	biological_process	amino acid biosynthetic process
L	0009073	biological_process	aromatic amino acid family biosynthetic process
L	0009423	biological_process	chorismate biosynthetic process
L	0016829	molecular_function	lyase activity
L	0019631	biological_process	quinate catabolic process

Functional Information from PROSITE/UniProt

site_id	PS01029
Number of Residues	18
Details	DEHYDROQUINASE_II Dehydroquinase class II signature. IHGPNLnlLGkREpevYG

Chain	Residue	Details
A	ILE8-GLY25

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	ACT_SITE: Proton acceptor => ECO:0000255\|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	TYR24
B	TYR24
C	TYR24
D	TYR24
E	TYR24
F	TYR24
G	TYR24
H	TYR24
I	TYR24
J	TYR24
K	TYR24
L	TYR24

site_id	SWS_FT_FI2
Number of Residues	12
Details	ACT_SITE: Proton donor => ECO:0000255\|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	HIS102
B	HIS102
C	HIS102
D	HIS102
E	HIS102
F	HIS102
G	HIS102
H	HIS102
I	HIS102
J	HIS102
K	HIS102
L	HIS102

site_id	SWS_FT_FI3
Number of Residues	60
Details	BINDING: BINDING => ECO:0000255\|HAMAP-Rule:MF_00169

Chain	Residue	Details
J	LEU103
J	ARG113
K	ASN76
K	HIS82
K	ASP89
K	LEU103
K	ARG113
L	ASN76
L	HIS82
L	ASP89
L	LEU103
L	ARG113
J	ASN76
J	HIS82
J	ASP89
A	ASN76
A	HIS82
A	ASP89
A	LEU103
A	ARG113
B	ASN76
B	HIS82
B	ASP89
B	LEU103
B	ARG113
C	ASN76
C	HIS82
C	ASP89
C	LEU103
C	ARG113
D	ASN76
D	HIS82
D	ASP89
D	LEU103
D	ARG113
E	ASN76
E	HIS82
E	ASP89
E	LEU103
E	ARG113
F	ASN76
F	HIS82
F	ASP89
F	LEU103
F	ARG113
G	ASN76
G	HIS82
G	ASP89
G	LEU103
G	ARG113
H	ASN76
H	HIS82
H	ASP89
H	LEU103
H	ARG113
I	ASN76
I	HIS82
I	ASP89
I	ARG113
I	LEU103

site_id	SWS_FT_FI4
Number of Residues	12
Details	SITE: Transition state stabilizer => ECO:0000255\|HAMAP-Rule:MF_00169

Chain	Residue	Details
A	ARG19
B	ARG19
C	ARG19
D	ARG19
E	ARG19
F	ARG19
G	ARG19
H	ARG19
I	ARG19
J	ARG19
K	ARG19
L	ARG19

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)