4H10
Intermolecular recognition revealed by the complex structure of human CLOCK-BMAL1 basic Helix-Loop-Helix domains with E-box DNA
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005667 | cellular_component | transcription regulator complex |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0046983 | molecular_function | protein dimerization activity |
| B | 0000981 | molecular_function | DNA-binding transcription factor activity, RNA polymerase II-specific |
| B | 0032922 | biological_process | circadian regulation of gene expression |
| B | 0046983 | molecular_function | protein dimerization activity |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 3 |
| 詳細 | SITE: Interaction with E-box DNA => ECO:0000269|PubMed:23229515 |
| 鎖名 | 残基 | 詳細 |
| B | ARG39 | |
| B | GLU43 | |
| B | ARG47 | |
| A | ARG85 |
| site_id | SWS_FT_FI2 |
| 残基数 | 1 |
| 詳細 | SITE: Important for interaction with BMAL1 => ECO:0000269|PubMed:23229515 |
| 鎖名 | 残基 | 詳細 |
| B | HIS84 |
| site_id | SWS_FT_FI3 |
| 残基数 | 2 |
| 詳細 | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:O08785 |
| 鎖名 | 残基 | 詳細 |
| B | SER38 | |
| B | SER42 |
| site_id | SWS_FT_FI4 |
| 残基数 | 2 |
| 詳細 | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO1) => ECO:0000250|UniProtKB:O08785 |
| 鎖名 | 残基 | 詳細 |
| B | LYS67 |
