4D5Y
Cryo-EM structures of ribosomal 80S complexes with termination factors and cricket paralysis virus IRES reveal the IRES in the translocated state
This is a non-PDB format compatible entry.
Functional Information from GO Data
Chain | GOid | namespace | contents |
a | 0003735 | molecular_function | structural constituent of ribosome |
a | 0005840 | cellular_component | ribosome |
a | 0006412 | biological_process | translation |
a | 0015934 | cellular_component | large ribosomal subunit |
A | 0002181 | biological_process | cytoplasmic translation |
A | 0003723 | molecular_function | RNA binding |
A | 0003735 | molecular_function | structural constituent of ribosome |
A | 0005737 | cellular_component | cytoplasm |
A | 0005840 | cellular_component | ribosome |
A | 0006412 | biological_process | translation |
A | 0015934 | cellular_component | large ribosomal subunit |
A | 0019843 | molecular_function | rRNA binding |
A | 0022625 | cellular_component | cytosolic large ribosomal subunit |
A | 0022626 | cellular_component | cytosolic ribosome |
A | 1990904 | cellular_component | ribonucleoprotein complex |
b | 0003735 | molecular_function | structural constituent of ribosome |
b | 0005840 | cellular_component | ribosome |
b | 0006412 | biological_process | translation |
B | 0003735 | molecular_function | structural constituent of ribosome |
B | 0005840 | cellular_component | ribosome |
B | 0006412 | biological_process | translation |
c | 0003723 | molecular_function | RNA binding |
c | 0003735 | molecular_function | structural constituent of ribosome |
c | 0022625 | cellular_component | cytosolic large ribosomal subunit |
C | 0003735 | molecular_function | structural constituent of ribosome |
C | 0005840 | cellular_component | ribosome |
C | 0006412 | biological_process | translation |
d | 0003735 | molecular_function | structural constituent of ribosome |
d | 0005840 | cellular_component | ribosome |
d | 0006412 | biological_process | translation |
D | 0003735 | molecular_function | structural constituent of ribosome |
D | 0005840 | cellular_component | ribosome |
D | 0006412 | biological_process | translation |
D | 0008097 | molecular_function | 5S rRNA binding |
e | 0003735 | molecular_function | structural constituent of ribosome |
e | 0005840 | cellular_component | ribosome |
e | 0006412 | biological_process | translation |
E | 0003735 | molecular_function | structural constituent of ribosome |
E | 0005840 | cellular_component | ribosome |
E | 0006412 | biological_process | translation |
f | 0003735 | molecular_function | structural constituent of ribosome |
f | 0005840 | cellular_component | ribosome |
f | 0006412 | biological_process | translation |
F | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
F | 0003723 | molecular_function | RNA binding |
F | 0003735 | molecular_function | structural constituent of ribosome |
g | 0003735 | molecular_function | structural constituent of ribosome |
g | 0005840 | cellular_component | ribosome |
g | 0006412 | biological_process | translation |
G | 0042254 | biological_process | ribosome biogenesis |
G | 1990904 | cellular_component | ribonucleoprotein complex |
h | 0000463 | biological_process | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
h | 0003735 | molecular_function | structural constituent of ribosome |
h | 0005840 | cellular_component | ribosome |
h | 0006412 | biological_process | translation |
h | 0022625 | cellular_component | cytosolic large ribosomal subunit |
H | 0003735 | molecular_function | structural constituent of ribosome |
H | 0005840 | cellular_component | ribosome |
H | 0006412 | biological_process | translation |
H | 0019843 | molecular_function | rRNA binding |
i | 0003735 | molecular_function | structural constituent of ribosome |
i | 0005840 | cellular_component | ribosome |
i | 0006412 | biological_process | translation |
I | 0003735 | molecular_function | structural constituent of ribosome |
I | 0005840 | cellular_component | ribosome |
I | 0006412 | biological_process | translation |
j | 0003735 | molecular_function | structural constituent of ribosome |
j | 0005840 | cellular_component | ribosome |
j | 0006412 | biological_process | translation |
J | 0003735 | molecular_function | structural constituent of ribosome |
J | 0005840 | cellular_component | ribosome |
J | 0006412 | biological_process | translation |
k | 0003735 | molecular_function | structural constituent of ribosome |
k | 0005840 | cellular_component | ribosome |
k | 0006412 | biological_process | translation |
l | 0003735 | molecular_function | structural constituent of ribosome |
l | 0005840 | cellular_component | ribosome |
l | 0006412 | biological_process | translation |
L | 0003735 | molecular_function | structural constituent of ribosome |
L | 0005840 | cellular_component | ribosome |
L | 0006412 | biological_process | translation |
m | 0003735 | molecular_function | structural constituent of ribosome |
m | 0005840 | cellular_component | ribosome |
m | 0006412 | biological_process | translation |
M | 0003723 | molecular_function | RNA binding |
M | 0003735 | molecular_function | structural constituent of ribosome |
M | 0005840 | cellular_component | ribosome |
M | 0006412 | biological_process | translation |
n | 0003735 | molecular_function | structural constituent of ribosome |
n | 0005840 | cellular_component | ribosome |
n | 0006412 | biological_process | translation |
N | 0003735 | molecular_function | structural constituent of ribosome |
N | 0005840 | cellular_component | ribosome |
N | 0006412 | biological_process | translation |
o | 0003735 | molecular_function | structural constituent of ribosome |
o | 0005840 | cellular_component | ribosome |
o | 0006412 | biological_process | translation |
O | 0003735 | molecular_function | structural constituent of ribosome |
O | 0005840 | cellular_component | ribosome |
O | 0006412 | biological_process | translation |
O | 0015934 | cellular_component | large ribosomal subunit |
p | 0003735 | molecular_function | structural constituent of ribosome |
p | 0005840 | cellular_component | ribosome |
p | 0006412 | biological_process | translation |
P | 0003735 | molecular_function | structural constituent of ribosome |
P | 0005840 | cellular_component | ribosome |
P | 0006412 | biological_process | translation |
P | 0015934 | cellular_component | large ribosomal subunit |
Q | 0003735 | molecular_function | structural constituent of ribosome |
Q | 0005840 | cellular_component | ribosome |
Q | 0006412 | biological_process | translation |
R | 0003723 | molecular_function | RNA binding |
R | 0003735 | molecular_function | structural constituent of ribosome |
R | 0005840 | cellular_component | ribosome |
R | 0006412 | biological_process | translation |
R | 0022625 | cellular_component | cytosolic large ribosomal subunit |
S | 0003735 | molecular_function | structural constituent of ribosome |
S | 0005840 | cellular_component | ribosome |
S | 0006412 | biological_process | translation |
t | 0003735 | molecular_function | structural constituent of ribosome |
t | 0005840 | cellular_component | ribosome |
t | 0006412 | biological_process | translation |
T | 0003735 | molecular_function | structural constituent of ribosome |
T | 0005840 | cellular_component | ribosome |
T | 0006412 | biological_process | translation |
u | 0003723 | molecular_function | RNA binding |
u | 0003735 | molecular_function | structural constituent of ribosome |
u | 0006412 | biological_process | translation |
u | 0015934 | cellular_component | large ribosomal subunit |
U | 0003735 | molecular_function | structural constituent of ribosome |
U | 0005840 | cellular_component | ribosome |
U | 0006412 | biological_process | translation |
V | 0003735 | molecular_function | structural constituent of ribosome |
V | 0005840 | cellular_component | ribosome |
V | 0006412 | biological_process | translation |
X | 0003735 | molecular_function | structural constituent of ribosome |
X | 0005840 | cellular_component | ribosome |
X | 0006412 | biological_process | translation |
X | 0019843 | molecular_function | rRNA binding |
Y | 0003723 | molecular_function | RNA binding |
Y | 0003735 | molecular_function | structural constituent of ribosome |
Y | 0005840 | cellular_component | ribosome |
Y | 0006412 | biological_process | translation |
Y | 0015934 | cellular_component | large ribosomal subunit |
Z | 0003735 | molecular_function | structural constituent of ribosome |
Z | 0005840 | cellular_component | ribosome |
Z | 0006412 | biological_process | translation |
Functional Information from PROSITE/UniProt
site_id | PS00049 |
Number of Residues | 27 |
Details | RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI |
Chain | Residue | Details |
V | ALA79-ILE105 |
site_id | PS00050 |
Number of Residues | 16 |
Details | RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV |
Chain | Residue | Details |
X | LYS134-VAL149 |
site_id | PS00051 |
Number of Residues | 17 |
Details | RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR |
Chain | Residue | Details |
l | LYS30-ARG46 |
site_id | PS00299 |
Number of Residues | 26 |
Details | UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD |
Chain | Residue | Details |
m | LYS27-ASP52 |
site_id | PS00358 |
Number of Residues | 17 |
Details | RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT |
Chain | Residue | Details |
J | LEU40-THR56 |
site_id | PS00464 |
Number of Residues | 25 |
Details | RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL |
Chain | Residue | Details |
P | ARG126-LEU150 |
site_id | PS00467 |
Number of Residues | 12 |
Details | RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE |
Chain | Residue | Details |
A | PRO197-GLU208 |
site_id | PS00474 |
Number of Residues | 24 |
Details | RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR |
Chain | Residue | Details |
B | PHE211-ARG234 |
site_id | PS00475 |
Number of Residues | 32 |
Details | RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIksvG |
Chain | Residue | Details |
a | LYS110-GLY141 |
site_id | PS00526 |
Number of Residues | 20 |
Details | RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP |
Chain | Residue | Details |
R | GLN7-PRO26 |
site_id | PS00579 |
Number of Residues | 15 |
Details | RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV |
Chain | Residue | Details |
h | LYS43-VAL57 |
site_id | PS00580 |
Number of Residues | 21 |
Details | RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG |
Chain | Residue | Details |
e | PHE20-GLY40 |
site_id | PS00634 |
Number of Residues | 33 |
Details | RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI |
Chain | Residue | Details |
F | VAL108-ILE140 |
site_id | PS00687 |
Number of Residues | 8 |
Details | ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV |
Chain | Residue | Details |
C | GLY15-VAL22 |
site_id | PS00700 |
Number of Residues | 22 |
Details | RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK |
Chain | Residue | Details |
H | GLN163-LYS184 |
site_id | PS00709 |
Number of Residues | 25 |
Details | RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL |
Chain | Residue | Details |
c | SER24-LEU48 |
site_id | PS00783 |
Number of Residues | 24 |
Details | RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG |
Chain | Residue | Details |
O | VAL84-GLY107 |
site_id | PS00939 |
Number of Residues | 27 |
Details | RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH |
Chain | Residue | Details |
C | ASN116-HIS142 |
site_id | PS00993 |
Number of Residues | 21 |
Details | RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG |
Chain | Residue | Details |
c | GLU80-GLY100 |
site_id | PS01073 |
Number of Residues | 18 |
Details | RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD |
Chain | Residue | Details |
W | PHE8-ASP25 |
site_id | PS01077 |
Number of Residues | 20 |
Details | RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG |
Chain | Residue | Details |
j | GLY4-GLY23 |
site_id | PS01082 |
Number of Residues | 18 |
Details | RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG |
Chain | Residue | Details |
G | CYS174-GLY191 |
site_id | PS01104 |
Number of Residues | 15 |
Details | RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG |
Chain | Residue | Details |
L | ARG71-GLY85 |
site_id | PS01105 |
Number of Residues | 22 |
Details | RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP |
Chain | Residue | Details |
f | GLY72-PRO93 |
site_id | PS01106 |
Number of Residues | 18 |
Details | RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM |
Chain | Residue | Details |
Q | LYS49-MET66 |
site_id | PS01107 |
Number of Residues | 12 |
Details | RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF |
Chain | Residue | Details |
Z | GLY125-PHE136 |
site_id | PS01108 |
Number of Residues | 19 |
Details | RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV |
Chain | Residue | Details |
Y | ASP52-VAL70 |
site_id | PS01144 |
Number of Residues | 15 |
Details | RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG |
Chain | Residue | Details |
d | VAL62-GLY76 |
site_id | PS01145 |
Number of Residues | 14 |
Details | RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN |
Chain | Residue | Details |
g | THR15-ASN28 |
site_id | PS01170 |
Number of Residues | 19 |
Details | RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K |
Chain | Residue | Details |
E | ASN182-LYS200 |
site_id | PS01171 |
Number of Residues | 26 |
Details | RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG |
Chain | Residue | Details |
T | GLY37-GLY62 |
site_id | PS01172 |
Number of Residues | 12 |
Details | RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC |
Chain | Residue | Details |
o | LYS61-CYS72 |
site_id | PS01190 |
Number of Residues | 11 |
Details | RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK |
Chain | Residue | Details |
i | PRO52-LYS62 |
site_id | PS01194 |
Number of Residues | 24 |
Details | RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG |
Chain | Residue | Details |
N | ASP46-GLY69 |
site_id | PS01199 |
Number of Residues | 20 |
Details | RIBOSOMAL_L1 Ribosomal protein L1 signature. MqdIgryLGtvLGPRGkMPE |
Chain | Residue | Details |
u | MET111-GLU130 |
site_id | PS01257 |
Number of Residues | 22 |
Details | RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV |
Chain | Residue | Details |
I | ALA108-VAL129 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: (3S)-3-hydroxyhistidine => ECO:0000250|UniProtKB:P62917 |
Chain | Residue | Details |
A | HIS216 |
site_id | SWS_FT_FI2 |
Number of Residues | 5 |
Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250|UniProtKB:P62917 |
Chain | Residue | Details |
A | LYS42 | |
A | LYS149 | |
A | LYS234 | |
A | LYS250 |