2Y02
TURKEY BETA1 ADRENERGIC RECEPTOR WITH STABILISING MUTATIONS AND BOUND AGONIST CARMOTEROL
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0004935 | molecular_function | adrenergic receptor activity |
| A | 0004940 | molecular_function | beta1-adrenergic receptor activity |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0007189 | biological_process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| A | 0016020 | cellular_component | membrane |
| A | 0045823 | biological_process | positive regulation of heart contraction |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0004935 | molecular_function | adrenergic receptor activity |
| B | 0004940 | molecular_function | beta1-adrenergic receptor activity |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0007189 | biological_process | adenylate cyclase-activating G protein-coupled receptor signaling pathway |
| B | 0016020 | cellular_component | membrane |
| B | 0045823 | biological_process | positive regulation of heart contraction |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE NA A 701 |
| 鎖名 | 残基 |
| A | CYS192 |
| A | TYR193 |
| A | ASP195 |
| A | CYS198 |
| site_id | AC2 |
| 残基数 | 10 |
| 詳細 | BINDING SITE FOR RESIDUE Y01 A 401 |
| 鎖名 | 残基 |
| A | ILE214 |
| A | HOH2020 |
| B | ARG205 |
| B | ALA206 |
| B | ALA210 |
| A | GLU130 |
| A | ARG157 |
| A | VAL160 |
| A | ILE161 |
| A | THR164 |
| site_id | AC3 |
| 残基数 | 6 |
| 詳細 | BINDING SITE FOR RESIDUE Y01 A 402 |
| 鎖名 | 残基 |
| A | GLN73 |
| A | CYS85 |
| A | ARG155 |
| A | LYS159 |
| A | TRP166 |
| A | 2CV505 |
| site_id | AC4 |
| 残基数 | 10 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV A 501 |
| 鎖名 | 残基 |
| A | TRP181 |
| A | ASP184 |
| A | GLU185 |
| A | ASN204 |
| A | ALA206 |
| A | HOH2021 |
| B | VAL160 |
| B | THR164 |
| B | Y01401 |
| B | 2CV505 |
| site_id | AC5 |
| 残基数 | 2 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV A 502 |
| 鎖名 | 残基 |
| A | ALA227 |
| A | LEU289 |
| site_id | AC6 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV A 503 |
| 鎖名 | 残基 |
| A | ARG205 |
| A | PHE315 |
| B | ARG148 |
| B | ARG157 |
| B | Y01401 |
| site_id | AC7 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV A 504 |
| 鎖名 | 残基 |
| A | VAL51 |
| A | VAL326 |
| A | ALA334 |
| A | MET338 |
| site_id | AC8 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV A 505 |
| 鎖名 | 残基 |
| A | VAL160 |
| A | CYS163 |
| A | Y01402 |
| B | GLU185 |
| B | 2CV501 |
| site_id | AC9 |
| 残基数 | 15 |
| 詳細 | BINDING SITE FOR RESIDUE WHJ A 601 |
| 鎖名 | 残基 |
| A | TRP117 |
| A | ASP121 |
| A | ASP200 |
| A | PHE201 |
| A | ALA208 |
| A | SER211 |
| A | SER215 |
| A | PHE306 |
| A | PHE307 |
| A | ASN310 |
| A | PHE325 |
| A | VAL326 |
| A | ASN329 |
| A | TYR333 |
| A | HOH2010 |
| site_id | BC1 |
| 残基数 | 10 |
| 詳細 | BINDING SITE FOR RESIDUE Y01 B 401 |
| 鎖名 | 残基 |
| A | ARG205 |
| A | ALA206 |
| A | ILE209 |
| A | 2CV501 |
| A | 2CV503 |
| A | HOH2021 |
| B | GLU130 |
| B | ARG157 |
| B | VAL160 |
| B | ILE161 |
| site_id | BC2 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE Y01 B 402 |
| 鎖名 | 残基 |
| B | LEU78 |
| B | CYS85 |
| B | ARG155 |
| B | LYS159 |
| B | TRP166 |
| site_id | BC3 |
| 残基数 | 9 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV B 501 |
| 鎖名 | 残基 |
| A | VAL160 |
| A | THR164 |
| A | 2CV505 |
| B | HIS180 |
| B | TRP181 |
| B | ARG183 |
| B | ASP184 |
| B | GLU185 |
| B | ASN204 |
| site_id | BC4 |
| 残基数 | 3 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV B 502 |
| 鎖名 | 残基 |
| B | ILE238 |
| B | HIS286 |
| B | MET296 |
| site_id | BC5 |
| 残基数 | 2 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV B 503 |
| 鎖名 | 残基 |
| A | ARG157 |
| B | ARG205 |
| site_id | BC6 |
| 残基数 | 1 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV B 504 |
| 鎖名 | 残基 |
| B | LEU47 |
| site_id | BC7 |
| 残基数 | 5 |
| 詳細 | BINDING SITE FOR RESIDUE 2CV B 505 |
| 鎖名 | 残基 |
| A | GLU185 |
| A | 2CV501 |
| B | VAL160 |
| B | CYS163 |
| B | TRP166 |
| site_id | BC8 |
| 残基数 | 12 |
| 詳細 | BINDING SITE FOR RESIDUE WHJ B 601 |
| 鎖名 | 残基 |
| B | CYS199 |
| B | ASP200 |
| B | ALA208 |
| B | SER211 |
| B | SER215 |
| B | PHE306 |
| B | ASN310 |
| B | ASN329 |
| B | TYR333 |
| B | TRP117 |
| B | ASP121 |
| B | VAL125 |
UniProtにおけるモチーフ・データベースPROSITEからの機能情報
| site_id | PS00237 |
| 残基数 | 17 |
| 詳細 | G_PROTEIN_RECEP_F1_1 G-protein coupled receptors family 1 signature. ASIeTLCVIAIDRYLaI |
| 鎖名 | 残基 | 詳細 |
| A | ALA127-ILE143 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 56 |
| 詳細 | TRANSMEM: Helical; Name=1 |
| 鎖名 | 残基 | 詳細 |
| A | GLN39-GLY67 | |
| B | GLN39-GLY67 |
| site_id | SWS_FT_FI2 |
| 残基数 | 156 |
| 詳細 | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:18594507 |
| 鎖名 | 残基 | 詳細 |
| A | SER68-THR76 | |
| A | ASP138-ARG155 | |
| A | ARG232-ASN313 | |
| B | SER68-THR76 | |
| B | ASP138-ARG155 | |
| B | ARG232-ASN313 |
| site_id | SWS_FT_FI3 |
| 残基数 | 52 |
| 詳細 | TRANSMEM: Helical; Name=2 |
| 鎖名 | 残基 | 詳細 |
| A | ASN77-VAL103 | |
| B | ASN77-VAL103 |
| site_id | SWS_FT_FI4 |
| 残基数 | 80 |
| 詳細 | TOPO_DOM: Extracellular => ECO:0000269|PubMed:18594507 |
| 鎖名 | 残基 | 詳細 |
| A | ARG104-GLU115 | |
| A | HIS180-ARG205 | |
| A | CYS344-ASP348 | |
| B | ARG104-GLU115 | |
| B | HIS180-ARG205 | |
| B | CYS344-ASP348 |
| site_id | SWS_FT_FI5 |
| 残基数 | 42 |
| 詳細 | TRANSMEM: Helical; Name=3 |
| 鎖名 | 残基 | 詳細 |
| A | LEU116-ILE137 | |
| B | LEU116-ILE137 |
| site_id | SWS_FT_FI6 |
| 残基数 | 46 |
| 詳細 | TRANSMEM: Helical; Name=4 |
| 鎖名 | 残基 | 詳細 |
| A | ALA156-MET179 | |
| B | ALA156-MET179 |
| site_id | SWS_FT_FI7 |
| 残基数 | 50 |
| 詳細 | TRANSMEM: Helical; Name=5 |
| 鎖名 | 残基 | 詳細 |
| A | ALA206-TYR231 | |
| B | ALA206-TYR231 |
| site_id | SWS_FT_FI8 |
| 残基数 | 58 |
| 詳細 | TRANSMEM: Helical; Name=6 |
| 鎖名 | 残基 | 詳細 |
| A | VAL314-TYR343 | |
| B | VAL314-TYR343 |
| site_id | SWS_FT_FI9 |
| 残基数 | 44 |
| 詳細 | TRANSMEM: Helical; Name=7 |
| 鎖名 | 残基 | 詳細 |
| A | PHE349-HIS371 | |
| B | PHE349-HIS371 |
| site_id | SWS_FT_FI10 |
| 残基数 | 6 |
| 詳細 | BINDING: BINDING => ECO:0000269|PubMed:18594507, ECO:0007744|PDB:2VT4 |
| 鎖名 | 残基 | 詳細 |
| A | ASP121 | |
| A | SER211 | |
| A | LEU357 | |
| B | ASP121 | |
| B | SER211 | |
| B | LEU357 |
| site_id | SWS_FT_FI11 |
| 残基数 | 2 |
| 詳細 | LIPID: S-palmitoyl cysteine => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
