2XTE

Structure of the TBL1 tetramerisation domain

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Functional Information from GO Data

ChainGOidnamespacecontents
A0000118cellular_componenthistone deacetylase complex
A0072686cellular_componentmitotic spindle
A0005654cellular_componentnucleoplasm
A0005634cellular_componentnucleus
A0017053cellular_componenttranscriptional repressor complex
A0008013molecular_functionbeta-catenin binding
A0042393molecular_functionhistone binding
A0042802molecular_functionidentical protein binding
A0008022molecular_functionprotein C-terminus binding
A0019904molecular_functionprotein domain specific binding
A0003714molecular_functiontranscription corepressor activity
A0008134molecular_functiontranscription factor binding
A0044212molecular_functiontranscription regulatory region DNA binding
A0016575biological_processhistone deacetylation
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0090263biological_processpositive regulation of canonical Wnt signaling pathway
A0045944biological_processpositive regulation of transcription by RNA polymerase II
A0045893biological_processpositive regulation of transcription, DNA-templated
A0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
A0050821biological_processprotein stabilization
A0006508biological_processproteolysis
A0019216biological_processregulation of lipid metabolic process
A0006357biological_processregulation of transcription by RNA polymerase II
A0007605biological_processsensory perception of sound
B0000118cellular_componenthistone deacetylase complex
B0072686cellular_componentmitotic spindle
B0005654cellular_componentnucleoplasm
B0005634cellular_componentnucleus
B0017053cellular_componenttranscriptional repressor complex
B0008013molecular_functionbeta-catenin binding
B0042393molecular_functionhistone binding
B0042802molecular_functionidentical protein binding
B0008022molecular_functionprotein C-terminus binding
B0019904molecular_functionprotein domain specific binding
B0003714molecular_functiontranscription corepressor activity
B0008134molecular_functiontranscription factor binding
B0044212molecular_functiontranscription regulatory region DNA binding
B0016575biological_processhistone deacetylation
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0090263biological_processpositive regulation of canonical Wnt signaling pathway
B0045944biological_processpositive regulation of transcription by RNA polymerase II
B0045893biological_processpositive regulation of transcription, DNA-templated
B0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
B0050821biological_processprotein stabilization
B0006508biological_processproteolysis
B0019216biological_processregulation of lipid metabolic process
B0006357biological_processregulation of transcription by RNA polymerase II
B0007605biological_processsensory perception of sound
C0000118cellular_componenthistone deacetylase complex
C0072686cellular_componentmitotic spindle
C0005654cellular_componentnucleoplasm
C0005634cellular_componentnucleus
C0017053cellular_componenttranscriptional repressor complex
C0008013molecular_functionbeta-catenin binding
C0042393molecular_functionhistone binding
C0042802molecular_functionidentical protein binding
C0008022molecular_functionprotein C-terminus binding
C0019904molecular_functionprotein domain specific binding
C0003714molecular_functiontranscription corepressor activity
C0008134molecular_functiontranscription factor binding
C0044212molecular_functiontranscription regulatory region DNA binding
C0016575biological_processhistone deacetylation
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0090263biological_processpositive regulation of canonical Wnt signaling pathway
C0045944biological_processpositive regulation of transcription by RNA polymerase II
C0045893biological_processpositive regulation of transcription, DNA-templated
C0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
C0050821biological_processprotein stabilization
C0006508biological_processproteolysis
C0019216biological_processregulation of lipid metabolic process
C0006357biological_processregulation of transcription by RNA polymerase II
C0007605biological_processsensory perception of sound
D0000118cellular_componenthistone deacetylase complex
D0072686cellular_componentmitotic spindle
D0005654cellular_componentnucleoplasm
D0005634cellular_componentnucleus
D0017053cellular_componenttranscriptional repressor complex
D0008013molecular_functionbeta-catenin binding
D0042393molecular_functionhistone binding
D0042802molecular_functionidentical protein binding
D0008022molecular_functionprotein C-terminus binding
D0019904molecular_functionprotein domain specific binding
D0003714molecular_functiontranscription corepressor activity
D0008134molecular_functiontranscription factor binding
D0044212molecular_functiontranscription regulatory region DNA binding
D0016575biological_processhistone deacetylation
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0090263biological_processpositive regulation of canonical Wnt signaling pathway
D0045944biological_processpositive regulation of transcription by RNA polymerase II
D0045893biological_processpositive regulation of transcription, DNA-templated
D0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
D0050821biological_processprotein stabilization
D0006508biological_processproteolysis
D0019216biological_processregulation of lipid metabolic process
D0006357biological_processregulation of transcription by RNA polymerase II
D0007605biological_processsensory perception of sound
E0000118cellular_componenthistone deacetylase complex
E0072686cellular_componentmitotic spindle
E0005654cellular_componentnucleoplasm
E0005634cellular_componentnucleus
E0017053cellular_componenttranscriptional repressor complex
E0008013molecular_functionbeta-catenin binding
E0042393molecular_functionhistone binding
E0042802molecular_functionidentical protein binding
E0008022molecular_functionprotein C-terminus binding
E0019904molecular_functionprotein domain specific binding
E0003714molecular_functiontranscription corepressor activity
E0008134molecular_functiontranscription factor binding
E0044212molecular_functiontranscription regulatory region DNA binding
E0016575biological_processhistone deacetylation
E0000122biological_processnegative regulation of transcription by RNA polymerase II
E0090263biological_processpositive regulation of canonical Wnt signaling pathway
E0045944biological_processpositive regulation of transcription by RNA polymerase II
E0045893biological_processpositive regulation of transcription, DNA-templated
E0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
E0050821biological_processprotein stabilization
E0006508biological_processproteolysis
E0019216biological_processregulation of lipid metabolic process
E0006357biological_processregulation of transcription by RNA polymerase II
E0007605biological_processsensory perception of sound
F0000118cellular_componenthistone deacetylase complex
F0072686cellular_componentmitotic spindle
F0005654cellular_componentnucleoplasm
F0005634cellular_componentnucleus
F0017053cellular_componenttranscriptional repressor complex
F0008013molecular_functionbeta-catenin binding
F0042393molecular_functionhistone binding
F0042802molecular_functionidentical protein binding
F0008022molecular_functionprotein C-terminus binding
F0019904molecular_functionprotein domain specific binding
F0003714molecular_functiontranscription corepressor activity
F0008134molecular_functiontranscription factor binding
F0044212molecular_functiontranscription regulatory region DNA binding
F0016575biological_processhistone deacetylation
F0000122biological_processnegative regulation of transcription by RNA polymerase II
F0090263biological_processpositive regulation of canonical Wnt signaling pathway
F0045944biological_processpositive regulation of transcription by RNA polymerase II
F0045893biological_processpositive regulation of transcription, DNA-templated
F0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
F0050821biological_processprotein stabilization
F0006508biological_processproteolysis
F0019216biological_processregulation of lipid metabolic process
F0006357biological_processregulation of transcription by RNA polymerase II
F0007605biological_processsensory perception of sound
G0000118cellular_componenthistone deacetylase complex
G0072686cellular_componentmitotic spindle
G0005654cellular_componentnucleoplasm
G0005634cellular_componentnucleus
G0017053cellular_componenttranscriptional repressor complex
G0008013molecular_functionbeta-catenin binding
G0042393molecular_functionhistone binding
G0042802molecular_functionidentical protein binding
G0008022molecular_functionprotein C-terminus binding
G0019904molecular_functionprotein domain specific binding
G0003714molecular_functiontranscription corepressor activity
G0008134molecular_functiontranscription factor binding
G0044212molecular_functiontranscription regulatory region DNA binding
G0016575biological_processhistone deacetylation
G0000122biological_processnegative regulation of transcription by RNA polymerase II
G0090263biological_processpositive regulation of canonical Wnt signaling pathway
G0045944biological_processpositive regulation of transcription by RNA polymerase II
G0045893biological_processpositive regulation of transcription, DNA-templated
G0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
G0050821biological_processprotein stabilization
G0006508biological_processproteolysis
G0019216biological_processregulation of lipid metabolic process
G0006357biological_processregulation of transcription by RNA polymerase II
G0007605biological_processsensory perception of sound
H0000118cellular_componenthistone deacetylase complex
H0072686cellular_componentmitotic spindle
H0005654cellular_componentnucleoplasm
H0005634cellular_componentnucleus
H0017053cellular_componenttranscriptional repressor complex
H0008013molecular_functionbeta-catenin binding
H0042393molecular_functionhistone binding
H0042802molecular_functionidentical protein binding
H0008022molecular_functionprotein C-terminus binding
H0019904molecular_functionprotein domain specific binding
H0003714molecular_functiontranscription corepressor activity
H0008134molecular_functiontranscription factor binding
H0044212molecular_functiontranscription regulatory region DNA binding
H0016575biological_processhistone deacetylation
H0000122biological_processnegative regulation of transcription by RNA polymerase II
H0090263biological_processpositive regulation of canonical Wnt signaling pathway
H0045944biological_processpositive regulation of transcription by RNA polymerase II
H0045893biological_processpositive regulation of transcription, DNA-templated
H0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
H0050821biological_processprotein stabilization
H0006508biological_processproteolysis
H0019216biological_processregulation of lipid metabolic process
H0006357biological_processregulation of transcription by RNA polymerase II
H0007605biological_processsensory perception of sound
I0000118cellular_componenthistone deacetylase complex
I0072686cellular_componentmitotic spindle
I0005654cellular_componentnucleoplasm
I0005634cellular_componentnucleus
I0017053cellular_componenttranscriptional repressor complex
I0008013molecular_functionbeta-catenin binding
I0042393molecular_functionhistone binding
I0042802molecular_functionidentical protein binding
I0008022molecular_functionprotein C-terminus binding
I0019904molecular_functionprotein domain specific binding
I0003714molecular_functiontranscription corepressor activity
I0008134molecular_functiontranscription factor binding
I0044212molecular_functiontranscription regulatory region DNA binding
I0016575biological_processhistone deacetylation
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0090263biological_processpositive regulation of canonical Wnt signaling pathway
I0045944biological_processpositive regulation of transcription by RNA polymerase II
I0045893biological_processpositive regulation of transcription, DNA-templated
I0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
I0050821biological_processprotein stabilization
I0006508biological_processproteolysis
I0019216biological_processregulation of lipid metabolic process
I0006357biological_processregulation of transcription by RNA polymerase II
I0007605biological_processsensory perception of sound
J0000118cellular_componenthistone deacetylase complex
J0072686cellular_componentmitotic spindle
J0005654cellular_componentnucleoplasm
J0005634cellular_componentnucleus
J0017053cellular_componenttranscriptional repressor complex
J0008013molecular_functionbeta-catenin binding
J0042393molecular_functionhistone binding
J0042802molecular_functionidentical protein binding
J0008022molecular_functionprotein C-terminus binding
J0019904molecular_functionprotein domain specific binding
J0003714molecular_functiontranscription corepressor activity
J0008134molecular_functiontranscription factor binding
J0044212molecular_functiontranscription regulatory region DNA binding
J0016575biological_processhistone deacetylation
J0000122biological_processnegative regulation of transcription by RNA polymerase II
J0090263biological_processpositive regulation of canonical Wnt signaling pathway
J0045944biological_processpositive regulation of transcription by RNA polymerase II
J0045893biological_processpositive regulation of transcription, DNA-templated
J0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
J0050821biological_processprotein stabilization
J0006508biological_processproteolysis
J0019216biological_processregulation of lipid metabolic process
J0006357biological_processregulation of transcription by RNA polymerase II
J0007605biological_processsensory perception of sound
K0000118cellular_componenthistone deacetylase complex
K0072686cellular_componentmitotic spindle
K0005654cellular_componentnucleoplasm
K0005634cellular_componentnucleus
K0017053cellular_componenttranscriptional repressor complex
K0008013molecular_functionbeta-catenin binding
K0042393molecular_functionhistone binding
K0042802molecular_functionidentical protein binding
K0008022molecular_functionprotein C-terminus binding
K0019904molecular_functionprotein domain specific binding
K0003714molecular_functiontranscription corepressor activity
K0008134molecular_functiontranscription factor binding
K0044212molecular_functiontranscription regulatory region DNA binding
K0016575biological_processhistone deacetylation
K0000122biological_processnegative regulation of transcription by RNA polymerase II
K0090263biological_processpositive regulation of canonical Wnt signaling pathway
K0045944biological_processpositive regulation of transcription by RNA polymerase II
K0045893biological_processpositive regulation of transcription, DNA-templated
K0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
K0050821biological_processprotein stabilization
K0006508biological_processproteolysis
K0019216biological_processregulation of lipid metabolic process
K0006357biological_processregulation of transcription by RNA polymerase II
K0007605biological_processsensory perception of sound
L0000118cellular_componenthistone deacetylase complex
L0072686cellular_componentmitotic spindle
L0005654cellular_componentnucleoplasm
L0005634cellular_componentnucleus
L0017053cellular_componenttranscriptional repressor complex
L0008013molecular_functionbeta-catenin binding
L0042393molecular_functionhistone binding
L0042802molecular_functionidentical protein binding
L0008022molecular_functionprotein C-terminus binding
L0019904molecular_functionprotein domain specific binding
L0003714molecular_functiontranscription corepressor activity
L0008134molecular_functiontranscription factor binding
L0044212molecular_functiontranscription regulatory region DNA binding
L0016575biological_processhistone deacetylation
L0000122biological_processnegative regulation of transcription by RNA polymerase II
L0090263biological_processpositive regulation of canonical Wnt signaling pathway
L0045944biological_processpositive regulation of transcription by RNA polymerase II
L0045893biological_processpositive regulation of transcription, DNA-templated
L0043161biological_processproteasome-mediated ubiquitin-dependent protein catabolic process
L0050821biological_processprotein stabilization
L0006508biological_processproteolysis
L0019216biological_processregulation of lipid metabolic process
L0006357biological_processregulation of transcription by RNA polymerase II
L0007605biological_processsensory perception of sound
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Functional Information from PDB Data

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Functional Information from PDB atom coordinates for the "HETATM" binding sites

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Functional Information from PROSITE/UniProt

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Functional Information from SwissProt/UniProt

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Catalytic Information from CSA

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