2O8J
Human euchromatic histone methyltransferase 2
GO（遺伝子オントロジー）由来の情報
| 鎖名 | GO（遺伝子オントロジー）id | 名前空間 | 内容 |
| A | 0002039 | molecular_function | p53 binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| A | 0042054 | molecular_function | histone methyltransferase activity |
| B | 0002039 | molecular_function | p53 binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| B | 0042054 | molecular_function | histone methyltransferase activity |
| C | 0002039 | molecular_function | p53 binding |
| C | 0005634 | cellular_component | nucleus |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| C | 0042054 | molecular_function | histone methyltransferase activity |
| D | 0002039 | molecular_function | p53 binding |
| D | 0005634 | cellular_component | nucleus |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016279 | molecular_function | protein-lysine N-methyltransferase activity |
| D | 0042054 | molecular_function | histone methyltransferase activity |
PDBデータベースに由来する情報
| site_id | AC1 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1501 |
| 鎖名 | 残基 |
| A | CYS974 |
| A | CYS987 |
| A | CYS1017 |
| A | CYS1021 |
| site_id | AC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1502 |
| 鎖名 | 残基 |
| A | CYS980 |
| A | CYS1017 |
| A | CYS1023 |
| A | CYS1027 |
| site_id | AC3 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1503 |
| 鎖名 | 残基 |
| A | CYS976 |
| A | CYS980 |
| A | CYS985 |
| A | CYS974 |
| site_id | AC4 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN A 1504 |
| 鎖名 | 残基 |
| A | CYS1115 |
| A | CYS1168 |
| A | CYS1170 |
| A | CYS1175 |
| site_id | AC5 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1505 |
| 鎖名 | 残基 |
| B | CYS974 |
| B | CYS987 |
| B | CYS1017 |
| B | CYS1021 |
| site_id | AC6 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1506 |
| 鎖名 | 残基 |
| B | CYS980 |
| B | CYS1017 |
| B | CYS1023 |
| B | CYS1027 |
| site_id | AC7 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1507 |
| 鎖名 | 残基 |
| B | CYS974 |
| B | CYS976 |
| B | CYS980 |
| B | CYS985 |
| site_id | AC8 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN B 1508 |
| 鎖名 | 残基 |
| B | CYS1115 |
| B | CYS1168 |
| B | CYS1170 |
| B | CYS1175 |
| site_id | AC9 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1509 |
| 鎖名 | 残基 |
| C | CYS974 |
| C | CYS987 |
| C | CYS1017 |
| C | CYS1021 |
| site_id | BC1 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1510 |
| 鎖名 | 残基 |
| C | CYS980 |
| C | CYS1017 |
| C | CYS1023 |
| C | CYS1027 |
| site_id | BC2 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1511 |
| 鎖名 | 残基 |
| C | CYS974 |
| C | CYS976 |
| C | CYS980 |
| C | CYS985 |
| site_id | BC3 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN C 1512 |
| 鎖名 | 残基 |
| C | CYS1115 |
| C | CYS1168 |
| C | CYS1170 |
| C | CYS1175 |
| site_id | BC4 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN D 1513 |
| 鎖名 | 残基 |
| D | CYS974 |
| D | CYS987 |
| D | CYS1017 |
| D | CYS1021 |
| site_id | BC5 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN D 1514 |
| 鎖名 | 残基 |
| D | CYS980 |
| D | CYS1017 |
| D | CYS1023 |
| D | CYS1027 |
| site_id | BC6 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN D 1515 |
| 鎖名 | 残基 |
| D | CYS974 |
| D | CYS976 |
| D | CYS980 |
| D | CYS985 |
| site_id | BC7 |
| 残基数 | 4 |
| 詳細 | BINDING SITE FOR RESIDUE ZN D 1516 |
| 鎖名 | 残基 |
| D | CYS1115 |
| D | CYS1168 |
| D | CYS1170 |
| D | CYS1175 |
| site_id | BC8 |
| 残基数 | 16 |
| 詳細 | BINDING SITE FOR RESIDUE SAH A 1505 |
| 鎖名 | 残基 |
| A | MET1048 |
| A | TRP1050 |
| A | SER1084 |
| A | TYR1085 |
| A | ARG1109 |
| A | PHE1110 |
| A | ASN1112 |
| A | HIS1113 |
| A | TYR1154 |
| A | PHE1166 |
| A | THR1167 |
| A | CYS1168 |
| A | GLN1169 |
| A | HOH1658 |
| A | HOH1700 |
| A | HOH1719 |
| site_id | BC9 |
| 残基数 | 14 |
| 詳細 | BINDING SITE FOR RESIDUE SAH B 1509 |
| 鎖名 | 残基 |
| B | MET1048 |
| B | TRP1050 |
| B | SER1084 |
| B | TYR1085 |
| B | ARG1109 |
| B | ASN1112 |
| B | HIS1113 |
| B | TYR1154 |
| B | PHE1166 |
| B | CYS1168 |
| B | GLN1169 |
| B | HOH1630 |
| B | HOH1652 |
| B | HOH1715 |
| site_id | CC1 |
| 残基数 | 16 |
| 詳細 | BINDING SITE FOR RESIDUE SAH C 1513 |
| 鎖名 | 残基 |
| C | ASN1112 |
| C | HIS1113 |
| C | TYR1154 |
| C | THR1167 |
| C | CYS1168 |
| C | GLN1169 |
| C | HOH1614 |
| C | HOH1657 |
| C | HOH1689 |
| C | HOH1724 |
| C | HOH1779 |
| C | MET1048 |
| C | TRP1050 |
| C | TYR1085 |
| C | ARG1109 |
| C | PHE1110 |
| site_id | CC2 |
| 残基数 | 18 |
| 詳細 | BINDING SITE FOR RESIDUE SAH D 1517 |
| 鎖名 | 残基 |
| D | MET1048 |
| D | TRP1050 |
| D | SER1084 |
| D | TYR1085 |
| D | ARG1109 |
| D | PHE1110 |
| D | ASN1112 |
| D | HIS1113 |
| D | TYR1154 |
| D | PHE1166 |
| D | THR1167 |
| D | CYS1168 |
| D | GLN1169 |
| D | HOH1587 |
| D | HOH1647 |
| D | HOH1656 |
| D | HOH1712 |
| D | HOH1717 |
SwissProt/UniProtに記載されている蛋白質分子機能情報
| site_id | SWS_FT_FI1 |
| 残基数 | 68 |
| 詳細 | BINDING: |
| 鎖名 | 残基 | 詳細 |
| A | CYS974 | |
| A | MET1048 | |
| A | TYR1085 | |
| A | ASN1112 | |
| A | CYS1115 | |
| A | CYS1168 | |
| A | GLN1169 | |
| A | CYS1170 | |
| A | CYS1175 | |
| B | CYS974 | |
| B | CYS976 | |
| A | CYS976 | |
| B | CYS980 | |
| B | CYS985 | |
| B | CYS987 | |
| B | CYS1017 | |
| B | CYS1021 | |
| B | CYS1023 | |
| B | CYS1027 | |
| B | MET1048 | |
| B | TYR1085 | |
| B | ASN1112 | |
| A | CYS980 | |
| B | CYS1115 | |
| B | CYS1168 | |
| B | GLN1169 | |
| B | CYS1170 | |
| B | CYS1175 | |
| C | CYS974 | |
| C | CYS976 | |
| C | CYS980 | |
| C | CYS985 | |
| C | CYS987 | |
| A | CYS985 | |
| C | CYS1017 | |
| C | CYS1021 | |
| C | CYS1023 | |
| C | CYS1027 | |
| C | MET1048 | |
| C | TYR1085 | |
| C | ASN1112 | |
| C | CYS1115 | |
| C | CYS1168 | |
| C | GLN1169 | |
| A | CYS987 | |
| C | CYS1170 | |
| C | CYS1175 | |
| D | CYS974 | |
| D | CYS976 | |
| D | CYS980 | |
| D | CYS985 | |
| D | CYS987 | |
| D | CYS1017 | |
| D | CYS1021 | |
| D | CYS1023 | |
| A | CYS1017 | |
| D | CYS1027 | |
| D | MET1048 | |
| D | TYR1085 | |
| D | ASN1112 | |
| D | CYS1115 | |
| D | CYS1168 | |
| D | GLN1169 | |
| D | CYS1170 | |
| D | CYS1175 | |
| A | CYS1021 | |
| A | CYS1023 | |
| A | CYS1027 |
| site_id | SWS_FT_FI2 |
| 残基数 | 4 |
| 詳細 | SITE: Histone H3K9me binding => ECO:0000250 |
| 鎖名 | 残基 | 詳細 |
| A | TYR1067 | |
| B | TYR1067 | |
| C | TYR1067 | |
| D | TYR1067 |
