9SR8
Crystal structure of IL-17A in complex with compound 22
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X10SA |
| Synchrotron site | SLS |
| Beamline | X10SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2022-10-31 |
| Detector | DECTRIS EIGER X 16M |
| Wavelength(s) | 0.918808 |
| Spacegroup name | C 2 2 21 |
| Unit cell lengths | 64.565, 85.004, 119.898 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 59.950 - 2.565 |
| R-factor | 0.2346 |
| Rwork | 0.234 |
| R-free | 0.25390 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.900 |
| Data reduction software | autoPROC |
| Data scaling software | autoPROC |
| Phasing software | PHASER |
| Refinement software | BUSTER (2.11.8) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 59.949 | 2.610 |
| High resolution limit [Å] | 2.565 | 2.565 |
| Rmerge | 0.077 | 2.803 |
| Rmeas | 0.082 | 2.949 |
| Rpim | 0.026 | 0.909 |
| Number of reflections | 10892 | 521 |
| <I/σ(I)> | 15.9 | 0.9 |
| Completeness [%] | 100.0 | 100 |
| Redundancy | 10 | 10.4 |
| CC(1/2) | 0.999 | 0.353 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 293 | 0.1M citrate pH 5.5 10% PEG 10,000 12% isopropanol 10% ethylene glycol |
