9S71
Crystal structure of RXR alpha LBD bound to a partial agonist 35 and a coactivator fragment SRC1
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID23-2 |
| Synchrotron site | ESRF |
| Beamline | ID23-2 |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2025-07-17 |
| Detector | DECTRIS EIGER2 X 9M |
| Wavelength(s) | 0.8731 |
| Spacegroup name | P 32 2 1 |
| Unit cell lengths | 78.100, 78.100, 81.889 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 35.250 - 2.000 |
| R-factor | 0.1963 |
| Rwork | 0.195 |
| R-free | 0.22160 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.069 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Phasing software | PHASER |
| Refinement software | PHENIX (1.21.1_5286) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 35.250 | 2.110 |
| High resolution limit [Å] | 2.000 | 2.000 |
| Rmerge | 0.132 | 1.008 |
| Rmeas | 0.148 | |
| Rpim | 0.048 | 0.344 |
| Number of reflections | 19949 | 2793 |
| <I/σ(I)> | 10.82 | 2 |
| Completeness [%] | 100.0 | 99.86 |
| Redundancy | 9.4 | 9.5 |
| CC(1/2) | 0.998 | 0.730 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 277 | 18% PEG 4000 0.1 M MES pH 6.5 |
