9MZZ

Crystal structure of RIPK1 with compound 36

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2021-05-07
Detector	DECTRIS EIGER2 X 16M
Wavelength(s)	1.0000
Spacegroup name	P 21 21 21
Unit cell lengths	47.376, 96.077, 127.923
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	76.820 - 2.680
R-factor	0.22874
Rwork	0.226
R-free	0.27172
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.004
RMSD bond angle	1.390
Data reduction software	autoPROC
Data scaling software	autoPROC ((Version 1.1.7))
Refinement software	REFMAC (5.8.0267)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	76.823	2.890
High resolution limit [Å]	2.680	2.680
Number of reflections	13048	652
<I/σ(I)>	7.7
Completeness [%]	90.4
Redundancy	8.1
CC(1/2)	0.991	0.471

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		277	25% (w/v) PEG3350; 6 mM Gly3; 0,3 M NaF; 0.28 M NH4I