9MZX

Crystal structure of human RIPK1 with Compound 1

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	SLS BEAMLINE X10SA
Synchrotron site	SLS
Beamline	X10SA
Temperature [K]	100
Detector technology	PIXEL
Collection date	2020-06-26
Detector	DECTRIS EIGER X 16M
Wavelength(s)	0.9998
Spacegroup name	P 21 21 21
Unit cell lengths	50.407, 101.124, 130.664
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	79.970 - 2.530
R-factor	0.21707
Rwork	0.215
R-free	0.26284
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	1.534
Data reduction software	autoPROC
Data scaling software	autoPROC ((Version 1.1.7))
Refinement software	REFMAC (5.8.0155)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	79.970	79.970
High resolution limit [Å]	2.530	2.530
Number of reflections	18320	890
<I/σ(I)>	10.7
Completeness [%]	100.0
Redundancy	8.2
CC(1/2)	0.997	0.408

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		277	20% (w/v) PEG3350; 6 mM Gly3; 0.01 m NaAcetate pH 4.75; 0.12 M Na3Citrate; 0.28 M NH4I