9IXT

Crystal structure of TEAD3 YAP binding domain with compound 2

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	PAL/PLS BEAMLINE 11C
Synchrotron site	PAL/PLS
Beamline	11C
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-05-30
Detector	DECTRIS PILATUS 6M
Wavelength(s)	0.97
Spacegroup name	P 21 21 21
Unit cell lengths	46.180, 102.610, 148.710
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	28.960 - 2.500
R-factor	0.2093
Rwork	0.206
R-free	0.24920
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.294
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX (1.20.1_4487)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	28.960	2.589
High resolution limit [Å]	2.500	2.500
Rmerge	0.232	0.763
Number of reflections	25187	2466
<I/σ(I)>	13.22	4.22
Completeness [%]	99.6
Redundancy	12.7
CC(1/2)	0.994	0.896

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		300	0.1M HEPES pH 7.5, 0.2M Ammonium acetate, 18% PEG 3350