9FLR
Crystal structure of human Haspin (GSG2) kinase bound to MU1963
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06SA |
| Synchrotron site | SLS |
| Beamline | X06SA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2022-09-03 |
| Detector | DECTRIS EIGER X 16M |
| Wavelength(s) | 0.99999 |
| Spacegroup name | P 21 21 21 |
| Unit cell lengths | 70.045, 77.250, 86.158 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 44.490 - 1.910 |
| R-factor | 0.1732 |
| Rwork | 0.171 |
| R-free | 0.20866 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.009 |
| RMSD bond angle | 1.580 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | MOLREP |
| Refinement software | REFMAC (5.8.0419) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 44.490 | 1.950 |
| High resolution limit [Å] | 1.910 | 1.910 |
| Number of reflections | 37161 | 2392 |
| <I/σ(I)> | 18.4 | 1.8 |
| Completeness [%] | 99.8 | |
| Redundancy | 13.3 | |
| CC(1/2) | 1.000 | 0.782 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION | 278 | 60% MPD, 0.1M MIB pH 6.0 |
