8ZTX
Crystal Structure of Human Myt1 Kinase domain Bounded with compound 6b
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | CAMD BEAMLINE GCPCC |
| Synchrotron site | CAMD |
| Beamline | GCPCC |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2022-06-08 |
| Detector | DECTRIS PILATUS 300K |
| Wavelength(s) | 0.987 |
| Spacegroup name | P 21 2 21 |
| Unit cell lengths | 55.649, 58.668, 99.241 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 37.036 - 1.700 |
| R-factor | 0.182677177453 |
| Rwork | 0.181 |
| R-free | 0.21577 |
| Structure solution method | MOLECULAR REPLACEMENT |
| Starting model (for MR) | 3p1a |
| RMSD bond length | 0.017 |
| RMSD bond angle | 1.707 |
| Data reduction software | HKL-2000 |
| Data scaling software | HKL-2000 |
| Refinement software | PHENIX (1.9_1692+SVN) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 37.040 | 1.761 |
| High resolution limit [Å] | 1.700 | 1.700 |
| Number of reflections | 36423 | 36423 |
| <I/σ(I)> | 3.3 | |
| Completeness [%] | 99.8 | |
| Redundancy | 6.9 | |
| CC(1/2) | 0.528 | 0.528 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 6.5 | 277 | 0.8 M Ammonium sulfate,100 mM Sodium citrate,pH 5.5 |
