8ZBG

Crystal structure of TEAD3 YAP binding domain with compound 15

This is a non-PDB format compatible entry.

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	PAL/PLS BEAMLINE 5C (4A)
Synchrotron site	PAL/PLS
Beamline	5C (4A)
Temperature [K]	100
Detector technology	CCD
Collection date	2022-05-03
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.97
Spacegroup name	P 21 21 21
Unit cell lengths	46.230, 101.160, 148.850
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	28.990 - 2.670
R-factor	0.216
Rwork	0.214
R-free	0.26100
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.335
Data reduction software	XDS
Data scaling software	XDS
Phasing software	PHASER
Refinement software	PHENIX (1.20.1_4487)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	28.990	2.765
High resolution limit [Å]	2.670	2.670
Rmerge	0.035	0.328
Number of reflections	20559	2018
<I/σ(I)>	14.09	2.15
Completeness [%]	99.8
Redundancy	2
CC(1/2)	0.999	0.838

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		300	0.1M HEPES pH 7.5, 0.2M Ammonium acetate, 18% PEG 3350