8VI1
Crystal structure of c-Met-D1228N in complex with KIN-7615
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SPRING-8 BEAMLINE BL45XU |
| Synchrotron site | SPring-8 |
| Beamline | BL45XU |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2022-06-14 |
| Detector | DECTRIS PILATUS 6M |
| Wavelength(s) | 1.00000 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 73.660, 69.820, 78.060 |
| Unit cell angles | 90.00, 95.84, 90.00 |
Refinement procedure
| Resolution | 43.830 - 3.110 |
| R-factor | 0.2531 |
| Rwork | 0.251 |
| R-free | 0.29791 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.002 |
| RMSD bond angle | 0.610 |
| Data reduction software | XDS |
| Data scaling software | Aimless |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0352) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 43.830 | 3.320 |
| High resolution limit [Å] | 3.110 | 3.110 |
| Rmerge | 0.105 | 0.372 |
| Number of reflections | 11252 | 384 |
| <I/σ(I)> | 11.7 | |
| Completeness [%] | 78.3 | |
| Redundancy | 6.8 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 291 | 0.1M HEPES pH7.5, 12.5% PEG4000, 10% isopropanol |
