8V9B
Lipoprotein(a) Kringle IV domain 7 - Lp(a) KIV7 in complex with LY3441732
This is a non-PDB format compatible entry.
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | APS BEAMLINE 31-ID |
| Synchrotron site | APS |
| Beamline | 31-ID |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2017-08-21 |
| Detector | DECTRIS PILATUS3 6M |
| Wavelength(s) | 0.97931 |
| Spacegroup name | P 31 |
| Unit cell lengths | 49.271, 49.271, 63.824 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 20.230 - 1.190 |
| R-factor | 0.14253 |
| Rwork | 0.141 |
| R-free | 0.17477 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.450 |
| Data reduction software | MOSFLM |
| Data scaling software | SCALA |
| Phasing software | PHASER |
| Refinement software | REFMAC (5.8.0103) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 20.230 | 1.250 |
| High resolution limit [Å] | 1.190 | 1.190 |
| Number of reflections | 55431 | 6419 |
| <I/σ(I)> | 9 | |
| Completeness [%] | 94.3 | 84 |
| Redundancy | 5.8 | 5.3 |
| CC(1/2) | 0.997 | 0.672 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 6.5 | 294 | 1.6 M Magnesium Sulfate, 100 mM MES pH 6.5 |
