8PJI

MLLT1 in complex with compound 10a

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I24
Synchrotron site	Diamond
Beamline	I24
Temperature [K]	293
Detector technology	PIXEL
Collection date	2018-12-02
Detector	DECTRIS PILATUS 6M
Wavelength(s)	0.92
Spacegroup name	P 43 21 2
Unit cell lengths	49.532, 49.532, 132.120
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	39.660 - 1.700
R-factor	0.24453
Rwork	0.243
R-free	0.27665
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.010
RMSD bond angle	1.575
Data reduction software	XDS
Phasing software	PHASER
Refinement software	REFMAC (5.8.0267)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	39.660	1.761
High resolution limit [Å]	1.700	1.700
Rmerge	0.064
Rmeas	0.090
Number of reflections	18898	1838
<I/σ(I)>	6.37
Completeness [%]	99.9	99.29
Redundancy	2
CC(1/2)	0.983	0.392

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, SITTING DROP		293	100 mM Bis-Tris pH=7.0 150 mM AmSO4 Gradient 20-30% PEG3350