8FRV

LSD1-CoREST in complex with T17, short soaking

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID30B
Synchrotron site	ESRF
Beamline	ID30B
Temperature [K]	100
Detector technology	PIXEL
Collection date	2022-02-22
Detector	DECTRIS EIGER X 9M
Wavelength(s)	0.96770
Spacegroup name	I 2 2 2
Unit cell lengths	118.681, 178.655, 235.702
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	59.340 - 2.720
R-factor	0.2196
Rwork	0.219
R-free	0.24790
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.011
RMSD bond angle	1.438
Data reduction software	xia2
Data scaling software	xia2
Phasing software	PHASER
Refinement software	PHENIX (1.18.2_3874)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	59.340	2.770
High resolution limit [Å]	2.720	2.720
Number of reflections	67413	6660
<I/σ(I)>	9.6
Completeness [%]	100.0
Redundancy	13.9	14.5
CC(1/2)	0.997	0.311

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	6.5	298	1.2 Sodium/Potassium Tartrate, 100 mM ADA pH 6.5