Obsolete: 7U4V
Summary
| Title: | CRYSTAL STRUCTURE OF TYROSINE KINASE 2 JH2 (PSEUDO KINASE DOMAIN) COMPLEXED COMPOUND-2d AKA 6-CYCLOPROPANEAMIDO-4-{[3-METHOXY-4-(1-METHYL-1H-1,2,4-TRI AZOL-3-YL)PYRIDIN-2-YL]AMINO}-N-(2H)METHYLPYRIDAZINE-3-CARBOXAMIDE |
| Citation: | Xiao, Z.,Yang, M.G.,Liu, c.,Sherwood, T.,Gilmore, J.L.,Lin, J.,Li, P.,Wu, D.,Tokarski, J.S.,Li, S.,Cheng, L.,Xie, C.,Fan, J.,Dierks, E.,Strnad, J.,Cvijic, M.E.,Khan, J.A.,Ruzanov, M.,Gallela, M.,Khandelwal, P.,Dyckman, A.J.,Mathur, A.,Lombardo, L.,Macor, J.E.,Carter, P.H.,Aranabar, N.,Burke, J.R.,Weinstein, D.S. Structure Activity Relationship Study of Central Pyridine-derived TYK2 JH2 Inhibitors: Optimization of the PK Profile through C4 and C6 Variations To Be Published, |
| Experimental method: | X-RAY DIFFRACTION (3.04 Å) |
| Deposition date: | 2022-03-01 |
| Release date: | 2023-03-22 |
| Obsoletion date: | 2023-04-05 |
| Obsoletion details: | The company did not authorize release of the structure at this time. |
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 7u4v.cif.gz Display(111.38 KB) 7u4v.cif | ||
| PDBML | all | 7u4v.xml.gz Display(147.03 KB) 7u4v.xml | |
| PDB | pdb7u4v.ent.gz Display(86.82 KB) pdb7u4v.ent | ||
| Structure factors | r7u4vsf.ent.gz Display(455.62 KB) r7u4vsf.ent | ||
