6PX0

Crystal structure of the TPR domain of human aryl hydrocarbon receptor-interacting protein-like 1 (AIPL1)

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALS BEAMLINE 4.2.2
Synchrotron site	ALS
Beamline	4.2.2
Temperature [K]	100
Detector technology	CMOS
Collection date	2019-03-07
Detector	RDI CMOS_8M
Wavelength(s)	1.00
Spacegroup name	P 1 21 1
Unit cell lengths	37.750, 44.170, 52.530
Unit cell angles	90.00, 100.96, 90.00

Refinement procedure

Resolution	33.240 - 1.550
R-factor	0.1897
Rwork	0.188
R-free	0.22010
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	4aif
RMSD bond length	0.008
RMSD bond angle	0.997
Data scaling software	SCALA
Phasing software	PHASER
Refinement software	PHENIX (1.15.2_3472)

Data quality characteristics

	Overall	Outer shell
Low resolution limit [Å]	44.170	1.580
High resolution limit [Å]	1.550	1.550
Rmerge	0.038	0.689
Rmeas	0.045	0.045
Rpim	0.023	0.413
Number of reflections	24471	24471
<I/σ(I)>	25.6	2.4
Completeness [%]	98.6	100
Redundancy	6.9	6.9
CC(1/2)	1.000	0.860

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	0.1 M Tris, 5-15 % PEG 8000 pH-7.5-8.5