5FWT

Wnt modulator Kremen crystal form I at 2.10A

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I03
Synchrotron site	Diamond
Beamline	I03
Temperature [K]	100
Detector technology	PIXEL
Collection date	2015-04-15
Detector	DECTRIS PILATUS
Spacegroup name	P 31 2 1
Unit cell lengths	50.538, 50.538, 187.402
Unit cell angles	90.00, 90.00, 120.00

Refinement procedure

Resolution	62.470 - 2.100
R-factor	0.18466
Rwork	0.182
R-free	0.23223
Structure solution method	OTHER
Starting model (for MR)	NONE
RMSD bond length	0.021
RMSD bond angle	2.005
Data reduction software	XDS
Data scaling software	Aimless
Refinement software	REFMAC (5.8.0135)

Data quality characteristics

	Overall
Low resolution limit [Å]	62.470
High resolution limit [Å]	2.100
Rmerge	0.090
Number of reflections	17089
<I/σ(I)>	12
Completeness [%]	100.0
Redundancy	5.2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1		5.6		1.000 M (NH4)H2PO4 0.100 M NA3CITRATE PH 5.6