5FW8

Structure of human transthyretin mutant E89K

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALBA BEAMLINE XALOC
Synchrotron site	ALBA
Beamline	XALOC
Temperature [K]	100
Detector technology	CCD
Spacegroup name	P 21 2 21
Unit cell lengths	42.412, 65.587, 84.387
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	65.590 - 1.600
R-factor	0.17062
Rwork	0.169
R-free	0.20444
Structure solution method	OTHER
Starting model (for MR)	NONE
RMSD bond length	0.026
RMSD bond angle	2.121
Refinement software	REFMAC (5.5.0109)

Data quality characteristics

	Overall
Low resolution limit [Å]	42.410
High resolution limit [Å]	1.600
Rmerge	0.030
Number of reflections	31735
<I/σ(I)>	21.2
Completeness [%]	99.8
Redundancy	4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1