5FW7

Structure of human transthyretin mutant A109V

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ALBA BEAMLINE XALOC
Synchrotron site	ALBA
Beamline	XALOC
Temperature [K]	100
Detector technology	PIXEL
Detector	DECTRIS PILATUS 6M
Spacegroup name	P 21 21 2
Unit cell lengths	84.952, 43.925, 65.125
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	65.130 - 1.200
R-factor	0.16112
Rwork	0.160
R-free	0.18515
Structure solution method	OTHER
Starting model (for MR)	NONE
RMSD bond length	0.031
RMSD bond angle	2.425
Refinement software	REFMAC (5.5.0109)

Data quality characteristics

	Overall
Low resolution limit [Å]	42.480
High resolution limit [Å]	1.200
Rmerge	0.050
Number of reflections	71364
<I/σ(I)>	11
Completeness [%]	93.3
Redundancy	3.1

Crystallization Conditions

crystal ID	method	pH	temperature	details
1