4CWF

Human HSP90 alpha N-terminal domain in complex with an Aminotriazoloquinazoline inhibitor

Experimental procedure

実験手法	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU MICROMAX-007 HF
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2007-05-24
Detector	MAR scanner 345 mm plate
Spacegroup name	I 2 2 2
格子定数 [Å]	66.502, 90.325, 98.018
格子定数 [度]	90.00, 90.00, 90.00

精密化法

残基	66.370 - 2.000
R因子	0.20171
Rwork	0.200
R-free	0.23337
Structure solution method	OTHER
Starting model (for MR)	NONE
結合長の平均二乗偏差(RMSD) [Å]	0.010
結合角の平均二乗偏差(RMSD) [度]	1.435
Data reduction software	DENZO
Data scaling software	SCALEPACK
Refinement software	REFMAC (5.6.0117)

Quality characteristics

	Overall	Outer shell
分解能 [Å] (低)	30.000	2.070
分解能 [Å] (高)	2.000	2.000
Rmerge_l_obs	0.080	0.270
独立反射数	23787
<I/σ(I)>	13.8	4.3
完全性 [%]	96.9	85.8
冗長性	3.3

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1