4U5V

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	ESRF BEAMLINE ID14-4
Synchrotron site	ESRF
Beamline	ID14-4
Temperature [K]	100
Detector technology	CCD
Collection date	2013-09-28
Detector	ADSC QUANTUM 315r
Wavelength(s)	0.9763
Spacegroup name	P 21 21 21
Unit cell lengths	79.041, 90.828, 99.745
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	41.332 - 1.968
R-factor	0.2312
Rwork	0.230
R-free	0.25930
RMSD bond length	0.010
RMSD bond angle	1.752
Refinement software	PHENIX ((phenix.refine: dev_1702))

Data quality characteristics

	Overall
Low resolution limit [Å]	67.100
High resolution limit [Å]	1.950
Number of reflections	49375
<I/σ(I)>	13.6
Completeness [%]	96.8
Redundancy	4.3

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	see manuscript