4U5L

IMPORTIN-ALPHA MINOR NLS SITE INHIBITOR

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	DIAMOND BEAMLINE I24
Synchrotron site	Diamond
Beamline	I24
Temperature [K]	100
Detector technology	PIXEL
Collection date	2012-09-20
Detector	PSI PILATUS 6M
Wavelength(s)	0.9192
Spacegroup name	P 21 21 21
Unit cell lengths	78.896, 90.604, 100.409
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	19.833 - 2.530
R-factor	0.1836
Rwork	0.181
R-free	0.22210
RMSD bond length	0.009
RMSD bond angle	1.217
Refinement software	PHENIX ((phenix.refine: dev_1702))

Data quality characteristics

	Overall
Low resolution limit [Å]	19.833
High resolution limit [Å]	2.530
Number of reflections	24615
<I/σ(I)>	7.9
Completeness [%]	99.7
Redundancy	10.4

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP		291	see manuscript