4TYG
Structural analysis of the human Fibroblast Growth Factor Receptor 4 Kinase
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | SLS BEAMLINE X06DA |
| Synchrotron site | SLS |
| Beamline | X06DA |
| Temperature [K] | 100 |
| Detector technology | PIXEL |
| Collection date | 2013-12-04 |
| Detector | PSI PILATUS 6M |
| Wavelength(s) | 1.00000 |
| Spacegroup name | H 3 2 |
| Unit cell lengths | 159.398, 159.398, 92.226 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 79.700 - 2.400 |
| R-factor | 0.20439 |
| Rwork | 0.202 |
| R-free | 0.23811 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.007 |
| RMSD bond angle | 1.033 |
| Data reduction software | XDS |
| Data scaling software | XSCALE |
| Refinement software | REFMAC (5.6.0117) |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 79.700 | 2.560 |
| High resolution limit [Å] | 2.400 | 2.400 |
| Rmerge | 0.089 | 0.738 |
| Number of reflections | 17454 | |
| <I/σ(I)> | 0.121 | |
| Completeness [%] | 98.7 | 99.6 |
| Redundancy | 4.3 | 4.4 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 277.15 | 2.5 M Sodium acetate 0.1 M MES pH 6.5 |
