4D2V
Structure of MELK in complex with inhibitors
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU FR-E |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2009-10-15 |
| Detector | RIGAKU SATURN |
| Spacegroup name | P 1 |
| Unit cell lengths | 66.650, 75.860, 79.070 |
| Unit cell angles | 86.08, 69.45, 89.87 |
Refinement procedure
| Resolution | 48.690 - 2.450 |
| R-factor | 0.2945 |
| Rwork | 0.291 |
| R-free | 0.35700 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.011 |
| RMSD bond angle | 1.170 |
| Data reduction software | d*TREK |
| Data scaling software | d*TREK |
| Refinement software | BUSTER (2.11.5) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 48.000 |
| High resolution limit [Å] | 2.450 |
| Rmerge | 0.100 |
| Number of reflections | 53154 |
| <I/σ(I)> | 4.7 |
| Completeness [%] | 94.6 |
| Redundancy | 1.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
