3HFB
Crystal structure of human tryoptophan hydroxylase type 1 with LP-534193
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ALS BEAMLINE 4.2.2 |
| Synchrotron site | ALS |
| Beamline | 4.2.2 |
| Detector technology | CCD |
| Detector | NOIR-1 |
| Wavelength(s) | 1.00 |
| Spacegroup name | P 1 21 1 |
| Unit cell lengths | 47.354, 58.143, 56.625 |
| Unit cell angles | 90.00, 96.77, 90.00 |
Refinement procedure
| Resolution | ? - 1.920 |
| R-factor | 0.21803 |
| Rwork | 0.214 |
| R-free | 0.28857 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.009 |
| RMSD bond angle | 1.194 |
| Refinement software | REFMAC (5.2.0005) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 32.020 |
| High resolution limit [Å] | 1.920 |
| Number of reflections | 21271 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, HANGING DROP | 8.5 | 293.15 | pH 8.5 , VAPOR DIFFUSION, HANGING DROP, temperature 293.15 K |
