2XK2

Structure of HSP90 with small molecule inhibitor bound

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Temperature [K]	100
Spacegroup name	P 1 21 1
Unit cell lengths	53.903, 44.143, 53.816
Unit cell angles	90.00, 115.95, 90.00

Refinement procedure

Resolution	32.610 - 1.950
R-factor	0.1888
Rwork	0.185
R-free	0.25660
Structure solution method	OTHER
Starting model (for MR)	NONE
Refinement software	BUSTER-TNT (2.5.1)

Data quality characteristics

	Overall
Low resolution limit [Å]	32.640
High resolution limit [Å]	1.950
Rmerge	0.080
Number of reflections	16791
Completeness [%]	92.0
Redundancy	2.1

Crystallization Conditions

crystal ID	method	pH	temperature	details
1