2XDX
Structure of HSP90 with small molecule inhibitor bound
Experimental procedure
Experimental method | SINGLE WAVELENGTH |
Source type | ROTATING ANODE |
Temperature [K] | 100 |
Spacegroup name | P 1 21 1 |
Unit cell lengths | 52.439, 43.928, 53.080 |
Unit cell angles | 90.00, 114.38, 90.00 |
Refinement procedure
Resolution | 32.330 - 2.420 |
R-factor | 0.209 |
Rwork | 0.203 |
R-free | 0.33040 |
Structure solution method | OTHER |
Starting model (for MR) | NONE |
Refinement software | BUSTER-TNT (2.5.1) |
Data quality characteristics
Overall | |
Low resolution limit [Å] | 32.510 |
High resolution limit [Å] | 2.450 |
Rmerge | 0.120 |
Number of reflections | 8264 |
Completeness [%] | 92.1 |
Redundancy | 2.4 |
Crystallization Conditions
crystal ID | method | pH | temperature | details |
1 |