2W1D
Structure determination of Aurora Kinase in complex with inhibitor
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ESRF BEAMLINE ID14-4 |
| Synchrotron site | ESRF |
| Beamline | ID14-4 |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Detector | ADSC CCD |
| Spacegroup name | P 61 2 2 |
| Unit cell lengths | 83.008, 83.008, 169.719 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 54.850 - 2.970 |
| R-factor | 0.241 |
| Rwork | 0.236 |
| R-free | 0.30800 |
| Structure solution method | OTHER |
| Starting model (for MR) | NONE |
| RMSD bond length | 0.012 |
| RMSD bond angle | 1.438 |
| Refinement software | REFMAC (5.4.0069A) |
Data quality characteristics
| Overall | |
| Low resolution limit [Å] | 54.850 |
| High resolution limit [Å] | 2.970 |
| Rmerge | 0.060 |
| Number of reflections | 7085 |
| <I/σ(I)> | 5.6 |
| Completeness [%] | 98.1 |
| Redundancy | 4.2 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 |
