2QBP
Crystal structure of ptp1b-inhibitor complex
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | ROTATING ANODE |
| Source details | RIGAKU RU200 |
| Temperature [K] | 113 |
| Detector technology | IMAGE PLATE |
| Collection date | 2002-07-03 |
| Detector | RIGAKU RAXIS IV |
| Spacegroup name | P 31 2 1 |
| Unit cell lengths | 88.456, 88.456, 104.290 |
| Unit cell angles | 90.00, 90.00, 120.00 |
Refinement procedure
| Resolution | 20.000 - 2.500 |
| R-factor | 0.209 |
| Rwork | 0.209 |
| R-free | 0.24500 |
| Structure solution method | MOLECULAR REPLACEMENT |
| RMSD bond length | 0.009 |
| Data reduction software | DENZO |
| Phasing software | CNS |
| Refinement software | CNS |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 20.000 | 2.540 |
| High resolution limit [Å] | 2.500 | 2.500 |
| Number of reflections | 15847 | |
| Completeness [%] | 94.6 | 98.9 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | 7 | 17% PEG 4000, 0.15M MAGNESIUM CHLORIDE, 0.1M HEPES, VAPOR DIFFUSION, HANGING DROP, TEMPERATURE 278K, pH 7.00 |
