1UYG

Human Hsp90-alpha with 8-(2,5-dimethoxy-benzyl)-2-fluoro-9H-purin-6-ylamine

Experimental procedure

実験手法	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU RUH3R
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2003-01-15
Detector	RIGAKU RAXIS IV
Spacegroup name	I 2 2 2
格子定数 [Å]	66.651, 90.806, 98.723
格子定数 [度]	90.00, 90.00, 90.00

精密化法

残基	67.420 - 2.000
Rwork	0.183
R-free	0.21814
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	1yer
Data reduction software	d*TREK
Data scaling software	d*TREK
Phasing software	MOLREP
Refinement software	REFMAC

Quality characteristics

	Overall	Outer shell
分解能 [Å] (低)	30.000	2.050
分解能 [Å] (高)	1.950	1.950
Rmerge_l_obs	0.050	0.333
独立反射数	24040
<I/σ(I)>	8.8	1.7
完全性 [%]	95.0	67.2
冗長性	1.8	1.3

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1		6.5		25% PEG MME 2000, 0.1M NA CACODYLATE, PH6.5, 0.2M MGCL2., pH 6.50