1UYE

Human Hsp90-alpha with 8-(2-chloro-3,4,5-trimethoxy-benzyl)-9-pent-4-ylnyl-9H-purin-6-ylamine

Experimental procedure

実験手法	SINGLE WAVELENGTH
Source type	ROTATING ANODE
Source details	RIGAKU RUH3R
Temperature [K]	100
Detector technology	IMAGE PLATE
Collection date	2003-01-15
Detector	RAXIS IV
Spacegroup name	I 2 2 2
格子定数 [Å]	66.700, 90.755, 98.171
格子定数 [度]	90.00, 90.00, 90.00

精密化法

残基	67.420 - 2.000
Rwork	0.183
R-free	0.21814
Structure solution method	MOLECULAR REPLACEMENT
Starting model (for MR)	1yer
Data reduction software	d*TREK
Data scaling software	d*TREK
Phasing software	MOLREP
Refinement software	REFMAC

Quality characteristics

	Overall	Outer shell
分解能 [Å] (低)	30.000	2.100
分解能 [Å] (高)	2.000	2.000
Rmerge_l_obs	0.092	0.352
独立反射数	46520
<I/σ(I)>	6.8	1
完全性 [%]	93.6	72.1
冗長性	2.4	2.1

結晶化条件

結晶ID	方法	pH	温度	溶液条件
1		6.5		25% PEG MME 2000, 0.1M NA CACODYLATE, PH6.5, 0.2M MGCL2., pH 6.50