1ZOH
Crystal structure of protein kinase CK2 in complex with TBB-derivatives inhibitors
Experimental procedure
| Experimental method | SINGLE WAVELENGTH |
| Source type | SYNCHROTRON |
| Source details | ELETTRA BEAMLINE 5.2R |
| Synchrotron site | ELETTRA |
| Beamline | 5.2R |
| Temperature [K] | 100 |
| Detector technology | CCD |
| Collection date | 2004-04-04 |
| Detector | MARRESEARCH |
| Wavelength(s) | 1.2 |
| Spacegroup name | C 1 2 1 |
| Unit cell lengths | 143.560, 61.090, 44.690 |
| Unit cell angles | 90.00, 102.70, 90.00 |
Refinement procedure
| Resolution | 15.390 - 1.810 |
| R-factor | 0.165 |
| Rwork | 0.165 |
| R-free | 0.22080 |
| Structure solution method | AB INITIO |
| RMSD bond length | 0.007 |
| RMSD bond angle | 0.022 |
| Data reduction software | MOSFLM |
| Data scaling software | CCP4 ((SCALA)) |
| Phasing software | SHELX |
| Refinement software | SHELXL-97 |
Data quality characteristics
| Overall | Outer shell | |
| Low resolution limit [Å] | 15.390 | 1.900 |
| High resolution limit [Å] | 1.800 | 1.800 |
| Number of reflections | 31911 | |
| Completeness [%] | 93.0 | 81.5 |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | VAPOR DIFFUSION, SITTING DROP | 8 | 293 | PEG 4000, Sodium Acetate, TRIS, pH 8.0, VAPOR DIFFUSION, SITTING DROP, temperature 293K |
