1W5W

HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	MAX II BEAMLINE I711
Synchrotron site	MAX II
Beamline	I711
Temperature [K]	278
Spacegroup name	P 21 21 2
Unit cell lengths	58.333, 85.928, 46.769
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	23.780 - 1.800
R-factor	0.189
Rwork	0.189
R-free	0.21300
Structure solution method	MOLECULAR REPLACEMENT
RMSD bond length	0.005
RMSD bond angle	1.200
Refinement software	CNS (1.1)

Data quality characteristics

	Overall
Low resolution limit [Å]	27.900
High resolution limit [Å]	1.800
Rmerge	0.070
Number of reflections	21819
Completeness [%]	98.3
Redundancy	2

Crystallization Conditions

crystal ID	method	pH	temperature	details
1