1TTA
THE X-RAY CRYSTAL STRUCTURE REFINEMENTS OF NORMAL HUMAN TRANSTHYRETIN AND THE AMYLOIDOGENIC VAL30MET VARIANT TO 1.7 ANGSTROMS RESOLUTION
Experimental procedure
| Spacegroup name | P 21 21 2 |
| Unit cell lengths | 43.800, 86.220, 65.780 |
| Unit cell angles | 90.00, 90.00, 90.00 |
Refinement procedure
| Resolution | 5.000 - 1.700 |
| R-factor | 0.168 |
| RMSD bond length | 0.018 |
| RMSD bond angle | 0.500 |
| Refinement software | PROLSQ |
Data quality characteristics
| Overall | |
| Rmerge | 0.053 * |
Crystallization Conditions
| crystal ID | method | pH | temperature | details |
| 1 | Vapor diffusion * | 5.3 * | 22 * |
Crystallization Reagents in Literatures
| ID | crystal ID | solution | reagent name | concentration (unit) | details |
| 1 | 1 | drop | protein | 10 (mg/ml) | |
| 2 | 1 | reservoir | citrate | 200 (mM) | |
| 3 | 1 | reservoir | protein | 10 (mg/ml) | |
| 4 | 1 | reservoir | ammonium sulfate | 40 (%) |
