1R08

STRUCTURAL ANALYSIS OF ANTIVIRAL AGENTS THAT INTERACT WITH THE CAPSID OF HUMAN RHINOVIRUSES

Experimental procedure

Spacegroup name	P 21 3
Unit cell lengths	445.100, 445.100, 445.100
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	? - 3.000
R-factor	0.181 *
Refinement software	REAL-SPACE (REFINEMENT)

Data quality characteristics

	Overall
High resolution limit [Å]	3.000 *
Rmerge	0.108 *
Total number of observations	77182 *
Number of reflections	68181 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	7.2 *		Arnold, E., (1984) J.Mol.Biol., 177, 417. *

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	drop	virus	5 (mg/ml)
2	1	drop	PEG8000	0.125 (%(w/v))	or 0.25%(w/v)
3	1	drop		0.01 (M)
4	1	drop	Tris-HCl	0.01 (M)
5	1	reservoir	PEG8000	0.25 (%(w/v))	or 0.5%(w/v)
6	1	reservoir		0.02
7	1	reservoir	Tris-HCl	0.01 (M)