1INY

A SIALIC ACID DERIVED PHOSPHONATE ANALOG INHIBITS DIFFERENT STRAINS OF INFLUENZA VIRUS NEURAMINIDASE WITH DIFFERENT EFFICIENCIES

Experimental procedure

Spacegroup name	I 4 3 2
Unit cell lengths	184.860, 184.860, 184.860
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	8.000 - 2.400
R-factor	0.187
Rwork	0.187
RMSD bond length	0.018
RMSD bond angle	2.110
Phasing software	X-PLOR
Refinement software	X-PLOR

Data quality characteristics

	Overall
High resolution limit [Å]	2.380 *
Rmerge	0.166 *
Number of reflections	20761
Completeness [%]	75.9
Redundancy	3.97 *

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	Vapor diffusion, hanging drop *	6.6 *		NATIVE CRYSTALS SOAKED IN 10MM EPANA SOLUTION, PH 7.2.

Crystallization Reagents in Literatures

ID	crystal ID	solution	reagent name	concentration (unit)	details
1	1	reservoir	potassium phosphate	1.7 (M)